3-phenyl-3-propoxy-propionic acid | 99451-14-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-phenyl-3-propoxy-propionic acid
• 英文别名: β-Propyloxy-β-phenyl-propionsaeure；3-Phenyl-3-propoxy-propionsaeure；3-Phenyl-3-propoxypropanoic acid
• CAS: 99451-14-6
• 化学式: C₁₂H₁₆O₃
• 分子量: 208.257
• InChiKey: UUOWVLUGFZXMOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Pharmaceutical compositions and methods for anesthesiological applications
  申请人：Melt Pharmaceuticals, Inc.

  公开号：US10555952B2

  公开（公告）日：2020-02-11

  Pharmaceutical compositions and methods for inducing conscious sedation using such compositions are described, the compositions comprising a benzodiazepine-based compound, a NMDA antagonist, and optionally a β-blocker, antiemetic, an NSAID, and/or an antihistamine medication. Methods for fabricating the compositions and using them for anesthesiological applications are also described.

  描述了使用此类组合物诱导清醒镇静的药物组合物和方法，组合物包括苯二氮卓类化合物、NMDA拮抗剂，以及可选的β-受体阻滞剂、止吐药、非甾体抗炎药和/或抗组胺药物。此外，还介绍了制造这些组合物并将其用于麻醉学应用的方法。
• Tyrosine Derivatives As Ppar-Gamma-Modulators
  申请人：Serra Comas Carmen

  公开号：US20070276043A1

  公开（公告）日：2007-11-29

  Compounds of general formula I, and the salts and solvates thereof, wherein R1 represents the radical 2-benzoylphenylamino; R2 represents —(CH 2 ) s —N(COR 3 )-A-J-T or —(CH 2 ) S —N(R 4 )—B-J-T; and s, R3, R4, A, B, J and T have the meanings disclosed in the description. These compounds are PPARγ modulators and, therefore, are useful for the treatment or prevention of a condition or a disease mediated by these receptors.
• NEW TYROSINE DERIVATIVES AS PPARy MODULATORS
  申请人：SERRA COMAS Carmen

  公开号：US20090088438A1

  公开（公告）日：2009-04-02

  Compounds of general formula I, and the salts and solvates thereof, wherein R1 represents the radical 2-benzoylphenylamino; R2 represents —(CH 2 ) s —N(COR3)-A-J-T or —(CH 2 ) s —N(R4)-B-J-T; and s, R3, R4, A, B, J and T have the meanings disclosed herein. These compounds are PPARγ modulators and, therefore, are useful for the treatment or prevention of a condition or a disease mediated by these receptors.
• PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS
  申请人：IMPRIMIS PHARMACEUTICALS, INC.

  公开号：US20180303847A1

  公开（公告）日：2018-10-25

  Pharmaceutical compositions and methods for inducing conscious sedation using such compositions are described, the compositions comprising a benzodiazepine-based compound, a NMDA antagonist, and optionally a β-blocker, antiemetic, an NSAID, and/or an antihistamine medication. Methods for fabricating the compositions and using them for anesthesiological applications are also described.
• US7423172B2
  申请人：——

  公开号：US7423172B2

  公开（公告）日：2008-09-09