| 1446115-56-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• CAS: 1446115-56-5
• 化学式: C₂₅H₁₆N₂O₅
• 分子量: 424.412
• InChiKey: NPDJZBVEOSGBGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.58
• 重原子数：
  32.0
• 可旋转键数：
  2.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  95.5
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  、 copper dichloride 以 乙醇 、 水 为溶剂， 生成
  参考文献：
  名称：

  A selectively fluorescein-based colorimetric probe for detecting copper(II) ion

  摘要：

  A novel fluorescein derivative furfuraldehyde fluorescein hydrazone (FFH) has been synthesized by reacting fluorescein hydrazide with furfuraldehyde and characterized by H-1 NMR, C-13 NMR, MS and elemental analysis. Addition of Cu2+ to the solution of FFH results in a rapid color change from colorless to yellow together with an obvious new band appeared at 502 nm in the UV-vis absorption spectra. This change is attributed to the spirocycle form of FFH opened via coordination with Cu2+ in a 1:1 stoichiometry and their association constant is determined as 6.1 x 10(4) L mol(-1). Experimental results indicate that the FFH can provide a rapid, selective and sensitive response to Cu2+ with a linear dynamic range 6.6-330 mu mol/L. Common interferent ions do not show any interference on the Cu2+ determination. It is anticipated that FFH can be a good candidate probe and has potential application for Cu2+ determination in aqueous solution. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2013.11.096
• 作为产物：
  描述：

  在 乙二胺四乙酸 作用下， 生成
  参考文献：
  名称：

  A selectively fluorescein-based colorimetric probe for detecting copper(II) ion

  摘要：

  A novel fluorescein derivative furfuraldehyde fluorescein hydrazone (FFH) has been synthesized by reacting fluorescein hydrazide with furfuraldehyde and characterized by H-1 NMR, C-13 NMR, MS and elemental analysis. Addition of Cu2+ to the solution of FFH results in a rapid color change from colorless to yellow together with an obvious new band appeared at 502 nm in the UV-vis absorption spectra. This change is attributed to the spirocycle form of FFH opened via coordination with Cu2+ in a 1:1 stoichiometry and their association constant is determined as 6.1 x 10(4) L mol(-1). Experimental results indicate that the FFH can provide a rapid, selective and sensitive response to Cu2+ with a linear dynamic range 6.6-330 mu mol/L. Common interferent ions do not show any interference on the Cu2+ determination. It is anticipated that FFH can be a good candidate probe and has potential application for Cu2+ determination in aqueous solution. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2013.11.096