diisopropyl (2-methyl-1,3-diphenylcycloprop-2-en-1-yl)phosphonate | 1313370-89-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: diisopropyl (2-methyl-1,3-diphenylcycloprop-2-en-1-yl)phosphonate
• 英文别名: [2-Methyl-1-[oxido-di(propan-2-yloxy)phosphaniumyl]-3-phenylcycloprop-2-en-1-yl]benzene；[2-methyl-1-[oxido-di(propan-2-yloxy)phosphaniumyl]-3-phenylcycloprop-2-en-1-yl]benzene
• CAS: 1313370-89-6
• 化学式: C₂₂H₂₇O₃P
• 分子量: 370.428
• InChiKey: XSBNXJYLQLEFJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  41.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  碘苯 在 bis-triphenylphosphine-palladium(II) chloride 、 silver trifluoromethanesulfonate 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 2.08h， 生成 diisopropyl (2-methyl-1,3-diphenylcycloprop-2-en-1-yl)phosphonate
  参考文献：
  名称：

  Silver Triflate-Catalyzed Cyclopropenation of Internal Alkynes with Donor-/Acceptor-Substituted Diazo Compounds

  摘要：

  Silver triflate was found to be an efficient catalyst for the cyclopropenation of internal alkynes using donor-/acceptor-substituted diazo compounds as carbenoid precursors. Highly substituted cyclopropenes, which cannot be synthesized directly via rhodium(II)-catalyzed carbenoid chemistry, can now be readily accessed.

  DOI：

  10.1021/ol201503j

文献信息

• Silver Triflate-Catalyzed Cyclopropenation of Internal Alkynes with Donor-/Acceptor-Substituted Diazo Compounds
  作者：John F. Briones、Huw M. L. Davies

  DOI：10.1021/ol201503j

  日期：2011.8.5

  Silver triflate was found to be an efficient catalyst for the cyclopropenation of internal alkynes using donor-/acceptor-substituted diazo compounds as carbenoid precursors. Highly substituted cyclopropenes, which cannot be synthesized directly via rhodium(II)-catalyzed carbenoid chemistry, can now be readily accessed.