difluoro(1,1,2,2,3,3-hexafluoro-3-trifluoromethoxypropoxy)acetic acid | 919005-51-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: difluoro(1,1,2,2,3,3-hexafluoro-3-trifluoromethoxypropoxy)acetic acid
• 英文别名: perfluoro-3,7-dioxaoctanoic acid；Difluoro-(1,1,2,2,3,3-hexafluoro-3-trifluoromethoxy-propoxy)-acetic acid；2,2-difluoro-2-[1,1,2,2,3,3-hexafluoro-3-(trifluoromethoxy)propoxy]acetic acid
• CAS: 919005-51-9
• 化学式: C₆HF₁₁O₄
• 分子量: 346.054
• InChiKey: PPLSBOFDIUXJMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  15

反应信息

• 作为产物：
  描述：

  2,2-difluoro-2-(1,1,2,2,3,3-hexafluoro-3-trifluoromethoxy-propoxy)ethanol 在 sodium hypochlorite 、 2,2,6,6-四甲基哌啶氧化物 、 potassium bromide 作用下， 以 水 、 乙腈 为溶剂， 以87%的产率得到difluoro(1,1,2,2,3,3-hexafluoro-3-trifluoromethoxypropoxy)acetic acid
  参考文献：
  名称：

  TEMPO mediated oxidation of fluorinated alcohols to carboxylic acids

  摘要：

  Fluorinated carboxylic acids (3a-f) have been prepared in good yield by oxidizing the corresponding alcohols (2a-f) in the presence of TEMPO (1) as catalyst, using oxidants like bleach and oxygen. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2012.06.002

文献信息

• FLUORINATED ETHER URETHANES AND METHODS OF USING THE SAME
  申请人：Dams Rudolf J.

  公开号：US20110232530A1

  公开（公告）日：2011-09-29

  Compounds comprising end groups represented by formula (Rf-Q) a -X-(A-) b and compounds comprising the reaction product of components comprising a multifunctional isocyanate compound and a fluorinated compound represented by formula (Rf-Q) a -X—(Z) b . Each Rf is independently a partially fluorinated or fully fluorinated group selected from Rf A (O) 2 CHL′-(CF 2 ) n —; [Rf B —(O) 1 —C(L)H—CF 2 —O] m —W—; CF 3 CFH—O—(CF 2 ) p —; CF 3 —(O—CF 2 )Z—; and CF 3 —O—(CF 2 ) 3 —O—CF—. Methods of making an article having a surface using the fluorinated compounds and treated articles are also disclosed.

  本文描述了由式(Rf-Q)a-X-(A-)b表示的末端基团组成的化合物以及由多功能异氰酸酯化合物和式(Rf-Q)a-X—(Z)b表示的氟化合物反应产物组成的化合物。其中，每个Rf都是独立的部分氟化或完全氟化的基团，选自RfA(O)2CHL′-(CF2)n—; [RfB—(O)1—C(L)H—CF2—O]m—W—; CFH—O—(CF2)p—; CF3—(O—CF2)Z—; 和 —O—(CF2)3—O—CF—。还公开了使用这些氟化合物制备具有表面的物品的方法和处理过的物品。
• FLUORINATED ETHER COMPOSITIONS AND METHODS OF USING THE SAME
  申请人：Dams Rudolf J.

  公开号：US20100179262A1

  公开（公告）日：2010-07-15

  A composition including at least one first divalent unit represented by formula: Each Rf is independently selected from the group consisting of Rf a —(O) t —CHF—(CF 2 ) n —; [Rf a —(O) t —C(L)H—CF 2 —O] m —W—; Rf b- O—(CF 2 ) p- ; F(C k F 2k )—(O—C k F2 k ) P —O—CF 2 —; and CF 3 —O—(CF 2 ) 3 —(OCF(CF 3 )—CF 2 ) Z —O-L 1 -. Each Q is independently selected from the group consisting of a bond, —C(O)—N(R 1 )—, and —C(O)—O—. Each X is independently selected from the group consisting of alkylene and arylalkylene, wherein alkylene and arylalkylene are each optionally interrupted by at least one ether linkage and optionally terminated by —N(R 1 )—C(O)— or —O—C(O)—. R and R 1 are each independently selected from the group consisting of hydrogen and alkyl having from 1 to 4 carbon atoms. Rf a represents a partially or fully fluorinated alkyl group having from 1 to 10 carbon atoms and optionally interrupted with at least one oxygen atom. Rf b is selected from the group consisting of CF 3 CFH— and F(C j F2 j )-. Methods of reducing surface tension of a liquid, making foams, and treating a surface using the compositions are also disclosed.

  一种组合物，包括至少一个由以下式表示的第一二价单元：每个Rf独立地选择自Rfa—（O）t—CHF—（CF2）n—；[Rfa—（O）t—C（L）H—CF2—O] m—W—；Rfb-O-（CF2）p-；F（CkF2k）-（O—CkF2k）P-O-CF2-；以及CF3-O-（CF2）3-（OCF（ ）-CF2）Z-O-L1-的部分或完全氟化烷基，其中每个Q独立地选择自键，-C（O）-N（R1）-，和-C（O）-O-的群，每个X独立地选择自烷基和芳基烷基的群，其中烷基和芳基烷基可以由至少一个醚键中断并且可以由-N（R1）-C（O）-或-O-C（O）-终止，R和R1各自独立地选择自氢和具有1至4个碳原子的烷基的群，Rfa表示具有1至10个碳原子的部分或完全氟化烷基，且可以由至少一个氧原子中断。Rfb选择自 CFH-和F（CjF2j）-。还公开了使用该组合物减少液体表面张力、制造泡沫和处理表面的方法。
• METHODS OF PREPARING FLUORINATED CARBOXYLIC ACIDS AND THEIR SALTS
  申请人：Hintzer Klaus

  公开号：US20120184770A1

  公开（公告）日：2012-07-19

  A method for preparing fluorinated carboxylic acids and theirs salts is described comprising subjecting a fluorinated alcohol of the general formula (A): A-CH 2 —OH to at least one first and at least one second oxidizing agent to produce a highly fluorinated carboxylic acid or their salts of the general formula (B): A-COO M + , wherein M+ represents a cation and wherein A in formulas (A) and (B) is the same and A represents the residue: Rf-[0] p -CX″Y″-[0] m -CX′Y′-[0] n -CXY— wherein Rf represents a fluorinated alkyl residue which may or may not contain one or more catenary oxygen atoms, p, m and n are independently from each other either 1 or O, X, X′, X″, Y, Y′ and Y″ are independently from each other H, F, CF 3 , or C 2 F 5 with the proviso that not all of X, X′, X″, Y, Y′ and Y″ are H; or A represents the residue: R—CFX— wherein X and R are independently selected from a hydrogen, a halogen, or an alkyl, alkenyl, cycloalkyl, or aryl residue, which may or may not contain one or more fluorine atoms and which may or may not contain one or more catenary oxygen atoms; wherein said at least one first oxidizing agent is a compound that can be converted, by action of the second oxidizing agent, into a reactive species capable of oxidizing the fluorinated alcohol.

  本发明涉及一种制备氟代羧酸及其盐的方法，包括将通式（A）的氟代醇A-CH2-OH经过至少一种第一氧化剂和至少一种第二氧化剂处理，以产生通式（B）的高度氟化的羧酸或其盐，其中M+代表阳离子，A在式（A）和（B）中相同，A代表残基：Rf-[0]p-CX″Y″-[0]m-CX′Y′-[0]n-CXY—，其中Rf代表可能含有一个或多个链氧原子的氟代烷基残基，p、m和n彼此独立，均为1或O，X、X′、X″、Y、Y′和Y″彼此独立，为H、F、CF3或C2F5，但不是所有的X、X′、X″、Y、Y′和Y″都是H；或者A代表残基：R—CFX—，其中X和R独立选择氢、卤素或含有一个或多个氟原子和一个或多个链氧原子的烷基、烯基、环烷基或芳基残基。其中，所述至少一种第一氧化剂是一种化合物，可以通过第二氧化剂的作用转化为能够氧化氟代醇的反应性物种。
• FLUORINATED ETHER SILANES AND METHODS OF USING THE SAME
  申请人：Maurer Andreas R.

  公开号：US20110124532A1

  公开（公告）日：2011-05-26

  Fluorinated compounds represented by formula Rf-Q-X—[Si(R) f (R 1 ) 3-f ] g . Each Rf is independently a partially fluorinated or fully fluorinated group selected from Rf a -(O) r -CHF—(CF 2 ) n -; [Rf b -(O) t -C(L)H—CF 2 —O] m -W—; CF 3 CFH—O—(CF 2 ) p -; CF 3 —(O—CF 2 ) z -; and CF 3 —O—(CF 2 ) 3 —O—CF 2 —. Methods of treating a surface or a hydrocarbon-bearing formation using the fluorinated compounds and treated articles and treated hydrocarbon-bearing formations are also disclosed.

  化学式为Rf-Q-X-[Si（R）f（R1）3-f]g的氟化合物。每个Rf独立地选择自Rfa-（O）r-CHF-（CF2）n-; [Rfb-（O）t-C（L）H-CF2-O]m-W-; CFH-O-（CF2）p-; CF3-（O-CF2）z-; 和 -O-（CF2）3-O-CF2-的部分氟化或完全氟化基团。还公开了使用氟化合物处理表面或含碳氢化合物的地层的方法以及经过处理的物品和经过处理的含碳氢化合物地层。
• FLUORINATED ETHER COMPOUNDS AND METHODS OF USING THE SAME
  申请人：Dams Rudolf J.

  公开号：US20110124782A1

  公开（公告）日：2011-05-26

  Compounds represented by formula (Rf-Q-X) s —Z. Each Rf is independently a partially fluorinated or fully fluorinated group selected from Rf a -(O) r —CHF—(CF 2 ) n —; [Rf b -(O) t C(L)H—CF 2 —O] m —W—; CF 3 CFH—O—(CF 2 ) p —; CF 3 —(O—CF 2 ) z —; and CF 3 —O—(CF 2 ) 3 —O—CF 2 —. Methods of reducing surface tension of a liquid, making foams, and treating a surface using the compounds are also disclosed.

  化合物的化学式为(Rf-Q-X)s—Z。其中每个Rf都是独立选择自Rfa-(O)r—CHF—(CF2)n—；[Rfb-(O)tC(L)H—CF2—O]m—W—； CFH—O—(CF2)p—；CF3—(O—CF2)z—；和 —O—(CF2)3—O—CF2—的部分氟化或全氟化基团。本发明还公开了利用这些化合物降低液体表面张力、制备泡沫和处理表面的方法。