| 1312589-29-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1312589-29-9
• 化学式: C₃₀H₂₆O₆
• 分子量: 482.533
• InChiKey: KMRJCOQYKXDGNB-YDWXAUTNSA-N

反应信息

• 作为产物：
  描述：

  2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate 、 反式,反式-1,3-丁二烯-1,4-二羧酸 在 18-冠醚-6 、 potassium carbonate 作用下， 反应 1.5h， 生成
  参考文献：
  名称：

  A Non-fluorescent Derivative from Derivatizing trans, trans-Muconic Acid with 2-(2-Naphthoxy)ethyl-2-(piperidino)ethanesulfonate

  摘要：

  trans, trans-Muconic acid (MA) is a polar metabolite of benzene and used as a biomarker for monitoring human exposure to benzene. Because MA is a trace metabolite, sensitive method is required for its detection. In addition, MA is a highly polar compound with dicarboxyl functions that could incur unfavorable adsorption on silica-based stationary phase usually used for separation. To address these problems, we planned to derivatize MA with a fluorescent reagent 2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate to give a naphthoxy derivative of MA for improving detection sensitivity and chromatographic properties. Surprisingly, the resulting derivative shows no fluorescent activity (λex: 226 nm; λem: 350 nm). The negative results could be used as an instructive example for discussing on fluorescence quenching.

  DOI：

  10.1007/s10895-009-0560-1