2-[({4-[6-(3-methoxyphenyl)hex-1-yn-1-yl]-1-naphthyl}methyl)amino]ethyl dihydrogen phosphate | 1402908-73-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-[({4-[6-(3-methoxyphenyl)hex-1-yn-1-yl]-1-naphthyl}methyl)amino]ethyl dihydrogen phosphate
• 英文别名: 2-[[4-[6-(3-Methoxyphenyl)hex-1-ynyl]naphthalen-1-yl]methylamino]ethyl dihydrogen phosphate
• CAS: 1402908-73-9
• 化学式: C₂₆H₃₀NO₅P
• 分子量: 467.502
• InChiKey: CVSAXZQEEIMDFX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  33
• 可旋转键数：
  12
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  88
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• SUBSTITUTED BICYCLIC METHYL AMINE DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS
  申请人：Takeuchi Janet A.

  公开号：US20120264715A1

  公开（公告）日：2012-10-18

  The present invention relates to novel substituted bicyclic methyl amine derivatives which are useful as sphingosine-1-phosphate receptors modulators and useful for treating a wide variety of disorders associated with modulation of sphingosine-1-phosphate receptors.

  本发明涉及一种新型的取代双环甲基胺衍生物，其可用作鞘氨醇-1-磷酸受体调节剂，并可用于治疗与鞘氨醇-1-磷酸受体调节相关的各种疾病。
• SUBSTITUTED BICYCLIC METHYL AMINE DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS
  申请人：Allergan, Inc.

  公开号：US20130338109A1

  公开（公告）日：2013-12-19

  The present invention relates to novel substituted bicyclic methyl amine derivatives which are useful as sphingosine-1-phosphate receptors modulators and useful for treating a wide variety of disorders associated with modulation of sphingosine-1-phosphate receptors.
• US8513418B2
  申请人：——

  公开号：US8513418B2

  公开（公告）日：2013-08-20
• US8658623B2
  申请人：——

  公开号：US8658623B2

  公开（公告）日：2014-02-25