2-(4-(1,2,3-Thiadiazol-4-yl)benzyl)malonic acid | 1259766-15-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 2-(4-(1,2,3-Thiadiazol-4-yl)benzyl)malonic acid
• 英文别名: 2-[[4-(Thiadiazol-4-yl)phenyl]methyl]propanedioic acid
• CAS: 1259766-15-8
• 化学式: C₁₂H₁₀N₂O₄S
• 分子量: 278.288
• InChiKey: SRUZAFXBIRDSJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  129
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• PSEUDODIPEPTIDES AS MMP INHIBITORS
  申请人：Devel Laurent

  公开号：US20120309674A1

  公开（公告）日：2012-12-06

  The invention relates to compounds, in particular MMP inhibitors. The compounds of the invention have formula (1). The invention can be used in particular in the pharmaceutical field. The present invention also relates to labeled compounds of formula (2), and to the use thereof as contrast agents for detecting extracellular matrix metalloproteinases.