1-[(5-(dimethylamino)-naphthalene-1-sulfonylamino)ethyl]-4,7,10-tris[(3'-carboxyl)-1'-carboxypropyl]-1,4,7,10-tetraazacyclododecane | 357165-79-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-[(5-(dimethylamino)-naphthalene-1-sulfonylamino)ethyl]-4,7,10-tris[(3'-carboxyl)-1'-carboxypropyl]-1,4,7,10-tetraazacyclododecane
• CAS: 357165-79-8
• 化学式: C₃₇H₅₄N₆O₁₄S
• 分子量: 838.934
• InChiKey: PUXQYWOOLKBREP-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  terbium(III) chloride hexahydrate 、 1-[(5-(dimethylamino)-naphthalene-1-sulfonylamino)ethyl]-4,7,10-tris[(3'-carboxyl)-1'-carboxypropyl]-1,4,7,10-tetraazacyclododecane 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成
  参考文献：
  名称：

  pH Switched sensitisation of europium(III) by a dansyl group

  摘要：

  The Eu(III), Tb(III) and Y(III) complexes of an eight-coordinate ligand containing a pendant dansylamidoethyl group were synthesised. Reversible intramolecular binding of the dansylamide nitrogen was demonstrated by UV absorption and luminescence pH titration, although no sensitisation of the Eu(III) or Tb(III) luminescent emission was seen due to lack of population of the chromophore triplet state. However, sensitisation of Eu(III) was achieved by protonation of the dimethylamino group on the naphthyl ring. Deprotonation constants of the dimethylamino (pK(a1)) and dansylamido (pK(a2)) group were determined in 0.1 M NaCl. Values of pK(a1) 3.9 (ligand), 3.6 (Eu), 3.7 (Tb), 3.8 (Y) and pK(a2) (log K-MLH) 10.8 (ligand), 5.8 (Eu), 6.0 (Tb), 6.2 (Y) were obtained. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(01)00346-2