2-(2-Chinolyl)-3-hydroxychromon | 66155-24-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2-(2-Chinolyl)-3-hydroxychromon
• 英文别名: 3-Hydroxy-2--chromon；2-(quinolin-2-yl)-3-hydroxychromone；3-hydroxy-2-quinolin-2-yl-chromen-4-one；3-Hydroxy-2-quinolin-2-ylchromen-4-one
• CAS: 66155-24-6
• 化学式: C₁₈H₁₁NO₃
• 分子量: 289.29
• InChiKey: ZNZXJNBZDRGTIF-UHFFFAOYSA-N

物化性质

• 沸点：
  497.2±45.0 °C(Predicted)
• 密度：
  1.434±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  59.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  mercury(II) diacetate 、 2-(2-Chinolyl)-3-hydroxychromon 以 甲醇 为溶剂， 生成 、
  参考文献：
  名称：

  Mercury Ions Complexation with a Series of Heterocyclic Derivatives of 3-Hydroxychromone: Spectral Effects and Prospects for Ultrasensitive Hg²⁺ Probing

  摘要：

  Complexation of three 3-hydroxychromone derivatives bearing a nitrogen-containing heterocyclic moiety in the position 2 of the chromone bicycle - benzimidazole, quinoline, and 2,5-diphenyloxazole, with mercury(II) ions is reported. Formation of chelate complexes with the metal cations coordinated with the cavity formed by 3-OH and 4-C=O groups was shown, as well as the possibility of side moiety heteroatom participation in binding of metal ions. High sensitivity to mercury of 2,5-diphenyloxazole-substituted 3-hydroxychromone was elucidated, allowing to detect Hg2+ below the maximum permissible concentration for drinking water. This makes the above-mentioned compound a prospective basis for development of sensors for ultralow mercury concentration detection in water. Unusual fluorescence ignition of 2-(quinolin-2-yl)-3-hydroxychromone at low Hg2+ concentrations, rarely observed for heavy metals ions complexation with organic fluorescent ligands, was discussed.

  DOI：

  10.1021/jp110974n
• 作为产物：
  描述：

  1-(Chinolyl-2)-2-(2-hydroxy-benzoyl)-ethylen 在 hydroxide 、 双氧水 作用下， 生成 2-(2-Chinolyl)-3-hydroxychromon
  参考文献：
  名称：

  Synthesis of Certain Chalcones and 3-Hydroxychromones

  摘要：

  DOI：

  10.1021/jo01071a015