Synthesis of a Carboxamide Linked UBr∗UBrDimer–Duplex and Triplex Stabilities of the Corresponding Oligodeoxynucleotides
摘要:
A U-Br*U-Br dimer was synthesized by connecting the appropiate nucleoside monomers through a 5-atom carboxamide linkage. The dimer was incorporated in oligodeoxynucleotides and investigated for hybridization properties toward single and double stranded DNA.
Synthesis of a Carboxamide Linked UBr∗UBrDimer–Duplex and Triplex Stabilities of the Corresponding Oligodeoxynucleotides
摘要:
A U-Br*U-Br dimer was synthesized by connecting the appropiate nucleoside monomers through a 5-atom carboxamide linkage. The dimer was incorporated in oligodeoxynucleotides and investigated for hybridization properties toward single and double stranded DNA.