ethyl 2-oxo-1,3-dioxan-5-yl-carbamate | 1448705-65-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 英文名称: ethyl 2-oxo-1,3-dioxan-5-yl-carbamate
• 英文别名: ethyl N-(2-oxo-1,3-dioxan-5-yl)carbamate
• CAS: 1448705-65-4
• 化学式: C₇H₁₁NO₅
• 分子量: 189.168
• InChiKey: QFNAADBONNJROY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  73.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• POLYCARBONATES BEARING PENDANT PRIMARY AMINES FOR MEDICAL APPLICATIONS
  申请人：Hedrick James L.

  公开号：US20140072607A1

  公开（公告）日：2014-03-13

  An antimicrobial composition comprises an anionic drug and an amine polymer comprising a first repeat unit of formula (2): wherein a′ is an integer equal to 1 or 2, b′ is an integer equal to 1 or 2, and each R′ is an independent monovalent radical selected from the group consisting of hydrogen, methyl, ethyl, and combinations thereof. G′ is a divalent linking group selected from the group consisting of a single bond and groups comprising at least one carbon. X − is a negatively charged counterion. The drug and the amine polymer are bound by noncovalent interactions.

  一种抗微生物组合物包括一种阴离子药物和一种胺聚合物，该胺聚合物包括具有以下式（2）的第一重复单元：其中a'是等于1或2的整数，b'是等于1或2的整数，每个R'是从氢、甲基、乙基和它们的组合中选择的独立单价基团。G'是从单键和包含至少一个碳的基团中选择的二价连接基团。X-是带负电的对离子。药物和胺聚合物通过非共价相互作用结合。
• [EN] POLYCARBONATES BEARING PENDANT PRIMARY AMINES FOR MEDICAL APPLICATIONS<br/>[FR] POLYCARBONATES PORTANT DES AMINES PRIMAIRES LATÉRALES POUR DES APPLICATIONS MÉDICALES
  申请人：IBM

  公开号：WO2014042924A1

  公开（公告）日：2014-03-20

  An antimicrobial composition comprises an anionic drug and an amine polymer comprising a first repeat unit of formula (2); wherein a' is an integer equal to 1 or 2, b' is an integer equal to 1 or 2, and each R' is an independent monovalent radical selected from the group consisting of hydrogen, methyl, ethyl, and combinations thereof. G' is a divalent linking group selected from the group consisting of a single bond and groups comprising at least one carbon. X¯ is a negatively charged counterion. The drug and the amine polymer are bound by noncovalent interactions.

  一种抗微生物组合物包括一种阴离子药物和一种胺聚合物，该胺聚合物包括公式（2）的第一重复单元；其中a'是等于1或2的整数，b'是等于1或2的整数，每个R'是从氢、甲基、乙基和它们的组合中选取的独立一价基团。G'是从单键和至少含有一个碳的基团中选取的二价连接基团。X¯是带负电的对离子。药物和胺聚合物通过非共价相互作用结合。
• [EN] ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS<br/>[FR] POLYMÈRES FONCTIONNALISÉS PAR GUANIDINIUM ET THIOURONIUM ANTIMICROBIENS
  申请人：AGENCY SCIENCE TECH & RES

  公开号：WO2016186581A1

  公开（公告）日：2016-11-24

  Antimicrobial cationic polycarbonates and polyurethanes have been prepared comprising one or more pendent guanidinium and/or isothiouronium groups. Additionally, antimicrobial particles were prepared having a silica core linked to surface groups comprising a guanidinium and/or isothiouronium group. The cationic polymers and cationic particles can be potent antimicrobial agents against Gram-negative microbes, Gram-positive microbes, and/or fungi.

  已制备含有一个或多个侧链胍啉和/或异硫脲基团的抗菌阳离子聚碳酸酯和聚氨酯。此外，制备了含有硅核心的抗菌颗粒，其与表面基团相连，包括一个胍啉和/或异硫脲基团。这些阳离子聚合物和阳离子颗粒可以是对革兰氏阴性微生物、革兰氏阳性微生物和/或真菌具有强效抗菌作用的剂。
• Antimicrobial guanidinium and thiouronium functionalized polymers
  申请人：International Business Machines Corporation

  公开号：US10779539B2

  公开（公告）日：2020-09-22

  Antimicrobial cationic polycarbonates and polyurethanes have been prepared comprising one or more pendent guanidinium and/or isothiouronium groups. Additionally, antimicrobial particles were prepared having a silica core linked to surface groups comprising a guanidinium and/or isothiouronium group. The cationic polymers and cationic particles can be potent antimicrobial agents against Gram-negative microbes, Gram-positive microbes, and/or fungi.

  抗菌阳离子聚碳酸酯和聚氨酯由一个或多个悬垂胍基和/或异硫脲基团组成。此外，还制备了抗菌颗粒，其二氧化硅核心与由胍基和/或异硫脲基团组成的表面基团相连。阳离子聚合物和阳离子微粒对革兰氏阴性微生物、革兰氏阳性微生物和/或真菌具有强效抗菌作用。
• ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS
  申请人：International Business Machines Corporation

  公开号：US20160338356A1

  公开（公告）日：2016-11-24

  Antimicrobial cationic polycarbonates and polyurethanes have been prepared comprising one or more pendent guanidinium and/or isothiouronium groups. Additionally, antimicrobial particles were prepared having a silica core linked to surface groups comprising a guanidinium and/or isothiouronium group. The cationic polymers and cationic particles can be potent antimicrobial agents against Gram-negative microbes, Gram-positive microbes, and/or fungi.