8-Ureido-naphthol-(2) | 99984-75-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 8-Ureido-naphthol-(2)
• 英文别名: (7-Hydroxynaphthalen-1-yl)urea
• CAS: 99984-75-5
• 化学式: C₁₁H₁₀N₂O₂
• 分子量: 202.213
• InChiKey: QFAZXFWFSWXFMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  75.4
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• CAPSAICIN INHIBITORS FOR TREATING OBESITY AND RELATED DISORDERS
  申请人：NOVO NORDISK A/S

  公开号：EP1771162A2

  公开（公告）日：2007-04-11
• CAPSAICIN INHIBITORS FOR THE TREATMENT OF OBESITY-RELATED DISORDERS
  申请人：Xenia Pharma

  公开号：EP1771162B1

  公开（公告）日：2013-06-05
• Antimicrobial compositions
  申请人：Mookerjee Pradip

  公开号：US20070258996A1

  公开（公告）日：2007-11-08

  An antimicrobial composition, including a synergistic combination of three or more potentiating agents as an active ingredient. Each of the three or more potentiating agents may be selected from the following types of compounds: sequestering agents, carbohydrates, terpenes, terpenoids, peptides, alkaloids, plant-derived oils, dyes and stains, sulfonates, phenols, esters, fatty acids, and dibenzofuran derivatives. At least two of the three or more potentiating agents are not of the same type of compound. The antimicrobial composition may have strong antimicrobial efficacy in control of microorganisms having resistance to currently used antimicrobials.
• Antimicrobial Compositions
  申请人：MOOKERJEE Pradip

  公开号：US20080194518A1

  公开（公告）日：2008-08-14

  An antimicrobial composition, including a synergistic combination of three or more agents as an active ingredient. Each of the three or more potentiating agents can be selected from the following types of compounds: sequestering agents, carbohydrates and carbohydrate derivatives, terpenes/terpenoids, amines and amine derivatives, plant-derived oils, sulfonates, phenols, fatty acids, dibenzofuran derivatives, organo isothiocyanates, quaternary ammonium compounds, peroxides and peroxide donors, and macrolide polyenes. At least two of the three or more potentiating agents are not of the same type of compound. The antimicrobial composition can have strong antimicrobial efficacy in control of microorganisms having resistance to currently used antimicrobials.
• Inhibition of the Activity of the Capsaicin Receptor in the Treatment of Obesity or Obesity-Related Diseases and Disorders
  申请人：Gram Dorte Xenia

  公开号：US20080214574A1

  公开（公告）日：2008-09-04

  The present invention provides a method of treating diseases or disorders benefiting from inactivating or down regulating the activity of the capsaicin receptor in a mammal by inhibiting the activity of the capasaicin receptor. The present invention also provides a method of treating obesity and obesity-related diseases and disorders in a mammal by inhibiting the activity of the capasaicin receptor.