2,2'-(1,2'-binaphthyl-2,3'-diyl)dipyridine | 1151554-31-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,2'-(1,2'-binaphthyl-2,3'-diyl)dipyridine
• CAS: 1151554-31-2
• 化学式: C₃₀H₂₀N₂
• 分子量: 408.502
• InChiKey: AAHSRTTUCZPHAF-UHFFFAOYSA-N

物化性质

• 沸点：
  530.5±45.0 °C(predicted)
• 密度：
  1.201±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.78
• 重原子数：
  32.0
• 可旋转键数：
  3.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.78
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  2-(2-naphthyl)pyridine 在 碘 、 copper diacetate 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以26%的产率得到3,3'-di(pyridin-2-yl)-2,2'-binaphthalene
  参考文献：
  名称：

  Cu(II)-mediated oxidative dimerization of 2-phenylpyridine derivatives

  摘要：

  A Cu(II)/I-2-mecliated C-H bond activation is described. A variety of 2-phenylpyridine derivatives are oxidatively dimerized at the ortho-position of the phenyl ring in which a net loss of two hydrogen atoms results ill [lie formation of a biaryl compound via a double C-H activation/C-C bond-forming process. Moderate functional group tolerance was observed on both the aryl and the pyridyl rings. A single electron transfer (SET) or electrophilic metalation process for iodination followed by Ullmann Coupling Of the intermediate iodinated product is proposed as the operating mechanism for the dimerization process. (C) 2008 Published by Ekevier Ltd.

  DOI：

  10.1016/j.tet.2008.10.053