丙烯酸十二氟庚酯 | 20109-57-3

• 物质功能分类: 化学试剂 - 有机试剂 - 酯类
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 丙烯酸十二氟庚酯
• 英文名称: Acrylic acid 2,3,4,5,5,5-hexafluoro-2,4-bis-trifluoromethyl-pentyl ester
• 英文别名: Actyflon-G05；[2,3,4,5,5,5-hexafluoro-2,4-bis(trifluoromethyl)pentyl] prop-2-enoate
• CAS: 20109-57-3
• 化学式: C₁₀H₆F₁₂O₂
• 分子量: 386.137
• InChiKey: SQPVWJZAHUFSJY-UHFFFAOYSA-N

物化性质

• 沸点：
  86-87 °C(Press: 20-22 Torr)
• 密度：
  1.495±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  丙烯酸十二氟庚酯 、 二乙醇胺 以 乙腈 为溶剂， 反应 8.0h， 生成 [2,3,4,5,5,5-Hexafluoro-2,4-bis(trifluoromethyl)pentyl] 3-[bis(2-hydroxyethyl)amino]propanoate
  参考文献：
  名称：

  Studies on waterborne polyurethanes based on new medium length fluorinated diols

  摘要：

  A novel fluorinated diol 3-(bis-(N,N-dihydroxyethyl)) dodecafluoroheptyl acrylate (DEFA) was for the first time synthesized via Michael addition reaction between diethanolamine and dodecafluoroheptyl acrylate, followed by a series of waterborne fluorinated polyurethane emulsions IPDI-DEFA-PU synthesis using isophorone diisocyanate (IPDI), poly(tetramethylene oxide glycol) (PTMG), dimethylolpropionic acid (DMPA) and 1,4-butanediol (BDO) as main starting materials, and DEFA as a chain extender. The structure of DEFA and IPDI-DEFA-PU was confirmed by Fourier transform infrared (FTIR) spectroscopy and proton nuclear magnetic resonance (H-1 NMR). It was found that the fluorine content increased from 0 to 15.1%, and the particle size of emulsion increased from 102 nm to 260 nm, whereas the surface tension of latex film decreased from 42.9 mN/m to 16.5 mN/m; while the water contact angle increased from 710 to 104, the swelling ratio of latex film in water and cyclohexane decreased from 15.8% to 1.1% and from 28.8% to 3.4%, respectively. Meanwhile, water/organic solvent resistance and thermal stability, mechanical properties of IPDI-DEFA-PU were all improved. As tensile strength increased from 9 MPa to 15 MPa, extensibility decreased from 520% to 280%. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2015.02.015

文献信息

• Contact lens material
  申请人：Menicon Co., Ltd.

  公开号：EP0294515A2

  公开（公告）日：1988-12-14

  A contact lens material composed of a copolymer of a monomer mixture comprising, as essential monomers, from 5 to 20 parts by weight, based on 100 parts by weight of the total monomer mixture, of a hydrophilic monomer consisting of from 40 to 60 mol% of N-vinyl-2-pyrrolidone and from 40 to 60 mol% of metharylic acid and from 30 to 95 parts by weight, based on 100 parts by weight of the total monomer mixture, of at least one of a silicon-containing acrylate and a silicon-containing methacrylate.

  一种隐形眼镜材料，由一种单体混合物的共聚物组成，该单体混合物的基本单体包括：以总单体混合物 100 重量份计，5 至 20 重量份的亲水性单体（由 40 至 60 摩尔%的 N-乙烯基-2-吡咯烷酮和 40 至 60 摩尔%的甲基丙烯酸组成），以及以总单体混合物 100 重量份计，30 至 95 重量份的含硅丙烯酸酯和含硅甲基丙烯酸酯中的至少一种。
• Non-hydrous soft contact lens and process for producing the same
  申请人：CIBA-GEIGY AG

  公开号：EP0294976A2

  公开（公告）日：1988-12-14

  A non-hydrous soft contact lens comprising a copolymer comprising, as monomer units,: (a) from 33.9 to 89 mol % of an acrylate represented by the general formula (I) shown below; (b) from 4.9 to 65 mol % of a methacrylate represented by the general formula (II) shown below; (c) from 1 to 20 mol % of at least one selected from an unsaturated carboxylic acid and its particular esters; (d) from 0 to 20 mol % of a particular acrylic acid ester having a straight chain alkyl or fluoroalkyl group; (e) from 0 to 20 mol % of a methacrylic acid ester having a straight-chain alkyl group; (f) from 0.1 to 10 mol % of a crosslinking monomer. General formula (I): wherein R₁ is a particular straight-chain alkyl or fluoroalkyl group. General formula (II): wherein R₂ is a particular straight-chain fluoroalkyl group; and a process for preparing the same. This contact lens has good oxygen permeability, mechanical strength, etc.

  一种非水性软性隐形眼镜，由一种共聚物组成，共聚物的单体单元包括： 1： (a) 33.9 至 89 摩尔%的丙烯酸酯，如下文通式(I)所示； (b) 4.9 至 65 摩尔%的由下图所示通式(II)代表的甲基丙烯酸酯； (c) 1 至 20 摩尔%的至少一种选自不饱和羧酸及其特定酯类的物质； (d) 0 至 20 摩尔%的具有直链烷基或氟烷基的特定丙烯酸酯； (e) 0 至 20 摩尔%的具有直链烷基的甲基丙烯酸酯； (f) 0.1 至 10 摩尔%的交联单体。 通式(I)： 其中 R₁ 是特定的直链烷基或氟烷基。 通式 (II)： 其中 R₂ 是特定的直链氟烷基；以及制备该物质的工艺。这种隐形眼镜具有良好的透氧性和机械强度等。
• Oxygen permeable hard contact lens
  申请人：KURARAY CO., LTD.

  公开号：EP0387706A2

  公开（公告）日：1990-09-19

  The hard contact lenses of the present invention are, being formed of copolymers comprising as its essential components a siloxanylalkylamide unit and a monomer unit containing fluorine, excellent in oxygen permeability, wettability with water, resistance to soiling by protein, lipids or the like, transparency and mechanical strength.

  本发明的硬性隐形眼镜由共聚物构成，共聚物的主要成分是硅氧烷酰胺单元和含氟单体单元，具有优异的透氧性、水润湿性、抗蛋白质、脂类或类似物质的污染性、透明度和机械强度。
• Ocular lens material
  申请人：Menicon Co., Ltd.

  公开号：EP0524557A2

  公开（公告）日：1993-01-27

  An ocular lens material comprising a copolymer prepared by polymerizing a monomer mixture comprising, as main components, (A) 15 to 40 % by mole of a fluoroalkyl (silicon-containing alkyl) fumarate, (B) 35 to 55 % by mole of an N-vinyl lactam, (C) 3 to 30 % by mole of at least one of acrylic acid and methacrylic acid, and (D) 0.1 to 20 % by mole of a crosslinkable monomer. The ocular lens material is excellent in all of transparency, oxygen permeability, mechanical

  一种眼透镜材料，包含一种通过聚合单体混合物制备的共聚物，该单体混合物的主要成分包括：(A) 15%至 40%（以摩尔计）的氟烷基（含硅烷基）富马酸盐；(B) 35%至 55%（以摩尔计）的 N-乙烯内酰胺；(C) 3%至 30%（以摩尔计）的丙烯酸和甲基丙烯酸中的至少一种；以及 (D) 0.1%至 20%（以摩尔计）的可交联单体。这种眼球晶状体材料在透明度、透氧性、机械性能、抗菌性和抗氧化性等方面都非常出色。
• MATERIAL FOR INTRAOCULAR LENSES
  申请人：Menicon Co., Ltd.

  公开号：EP3461506A1

  公开（公告）日：2019-04-03

  An intraocular lens material disclosed in the present description includes an aromatic ring-containing acrylate structural unit, an alkoxyalkyl methacrylate structural unit including an alkoxy group having 4 or less carbon atoms, a hydrophilic structural unit based on a hydrophilic monomer, and a cross-linking structural unit based on a cross-linkable monomer.

  本说明中公开的眼内透镜材料包括含芳香环的丙烯酸酯结构单元、包括具有 4 个或更少碳原子的烷氧基的甲基丙烯酸烷氧基烷基酯结构单元、基于亲水单体的亲水结构单元以及基于可交联单体的交联结构单元。