| 202832-46-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• CAS: 202832-46-0
• 化学式: C₉H₂₈OSi₄
• 分子量: 264.663
• InChiKey: JQMLSLLQUQQTEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.39
• 重原子数：
  14.0
• 可旋转键数：
  4.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  二氧化碳 、 三(三甲基硅基)硅烷 在 cesium fluoride 作用下， 以 二甲基亚砜 为溶剂， 反应 18.0h， 生成 一氧化碳 、
  参考文献：
  名称：

  Efficient Fluoride-Catalyzed Conversion of CO₂ to CO at Room Temperature

  摘要：

  A protocol for the efficient and selective reduction of carbon dioxide to carbon monoxide has been developed. Remarkably, this oxygen abstraction step can be performed with only the presence of catalytic cesium fluoride and a stoichiometric amount of a disilane in DMSO at room temperature. Rapid reduction of CO2 to CO could be achieved in only 2 h, which was observed by pressure measurements. To quantify the amount of CO produced, the reduction was coupled to an aminocarbonylation reaction using the two-chamber system, COware. The reduction was not limited to a specific disilane, since (Ph2MeSi)(2) as well as (PhMe2Si)(2) and (Me3Si)(3)SiH exhibited similar reactivity. Moreover, at a slightly elevated temperature, other fluoride salts were able to efficiently catalyze the CO2 to CO reduction. Employing a nonhygroscopic fluoride source, KHF2, omitted the need for an inert atmosphere. Substituting the disilane with silylborane, (pinacolato)BSiMe2Ph, maintained the high activity of the system, whereas the structurally related bis(pinacolato)diboron could not be activated with this fluoride methodology. Furthermore, this chemistry could be adapted to C-13-isotope labeling of six pharmaceutically relevant compounds starting from (BaCO3)-C-13 in a newly developed three-chamber system.

  DOI：

  10.1021/ja502911e