[(6-fluoro-1H-indazol-3-yl)methyl]amine | 1226442-91-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 英文名称: [(6-fluoro-1H-indazol-3-yl)methyl]amine
• 英文别名: (6-fluoro-2H-indazol-3-yl)methanamine
• CAS: 1226442-91-6
• 化学式: C₈H₈FN₃
• mdl: MFCD16631896
• 分子量: 165.17
• InChiKey: WHNKYDOGHWSDBL-UHFFFAOYSA-N

物化性质

• 沸点：
  355.4±27.0 °C(Predicted)
• 密度：
  1.384±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.125
• 拓扑面积：
  54.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS
  申请人：Boehringer Ingelheim International GmbH

  公开号：US20170320838A1

  公开（公告）日：2017-11-09

  The invention relates to morpholine and 1,4-oxazepane amide derivatives of general formula (I), which are agonists of somatostatin receptor subtype 4 (SSTR4), useful for preventing or treating medical disorders related to SSTR4. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture of the compounds according to the invention.