2-Methylindolizin-1-carbonsaeureethylester | 36944-70-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯并吡啶类
• 英文名称: 2-Methylindolizin-1-carbonsaeureethylester
• 英文别名: 2-Methylindolizin-8-carbonsaeureethylester；2-Methyl-8-ethoxycarbonylindolizin；2-methyl-indolizine-8-carboxylic acid ethyl ester；ethyl 2-methyl-8-indolizinecarboxylate；2-Methyl-8-carbethoxyindolizine；ethyl 2-methylindolizine-8-carboxylate
• CAS: 36944-70-4
• 化学式: C₁₂H₁₃NO₂
• 分子量: 203.241
• InChiKey: IWOBESRJJMVGDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• HETEROARYL AMIDE ANALOGUES AS P2X7 ANTAGONISTS
  申请人：Ihle David C.

  公开号：US20100266509A1

  公开（公告）日：2010-10-21

  Heteroaryl amide analogues are provided, of Formula (I), wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

  提供了异芳基酰胺类似物，其化学式为（I），其中变量如本文所述。这些化合物是配体，可用于体内或体外调节特定受体活性，并在治疗人类、家养伴侣动物和家畜动物的与病理受体激活相关的疾病方面特别有用。提供了用于治疗此类疾病的制药组合物和方法，以及用于受体定位研究的配体使用方法。
• Indolizine derivatives, compositions comprising at least one coupler chosen from indolizine derivatives and at least one oxidation base, and methods for using same
  申请人：——

  公开号：US20020002749A1

  公开（公告）日：2002-01-10

  Compositions for oxidation dyeing of keratin fibers comprising at least one oxidation base and at least one coupler chosen from indolizine derivatives, methods for using the same for oxidation dyeing of keratin fibers, and compounds chosen from indolizine derivatives.

  由至少一种氧化基和至少一种选自吲哚利嗪衍生物的耦合剂组成的用于角蛋白纤维氧化染色的组合物，使用该组合物对角蛋白纤维进行氧化染色的方法，以及选自吲哚利嗪衍生物的化合物。
• US6572664B2
  申请人：——

  公开号：US6572664B2

  公开（公告）日：2003-06-03
• US8580812B2
  申请人：——

  公开号：US8580812B2

  公开（公告）日：2013-11-12