4,4'-Methylene-bis(3-hydroxy-2-naphthalene carboxylic hydrazide) | 259142-70-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4,4'-Methylene-bis(3-hydroxy-2-naphthalene carboxylic hydrazide)
• 英文别名: 4-[[3-(Hydrazinecarbonyl)-2-hydroxynaphthalen-1-yl]methyl]-3-hydroxynaphthalene-2-carbohydrazide
• CAS: 259142-70-6
• 化学式: C₂₃H₂₀N₄O₄
• 分子量: 416.436
• InChiKey: UIOCOZOCKCVVQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  31
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  151
• 氢给体数：
  6
• 氢受体数：
  6

文献信息

• Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical
  申请人：K.U. LEUVEN RESEARCH & DEVELOPMENT

  公开号：EP0998946A1

  公开（公告）日：2000-05-10

  The invention relates to a non porphyrin compound or a pharmaceutically acceptable salt thereof, suitable for in vitro, in vivo and/or ex vivo use as a diagnosticum and/or pharmaceutical, said compound comprising: a targeting agent for targeting a specific area, such as an organ and/or tissue, a labelling agent L for labelling the targeted area; said targeting agent being connected to the labelling agent L, wherein said targeting agent comprises one or more substituted and/or unsubstituted organic ring compounds.

  本发明涉及一种非卟啉化合物或其药学上可接受的盐，适用于体外、体内和/或体外诊断和/或制药，所述化合物包括 靶向剂，用于靶向特定区域，如器官和/或组织、 用于标记目标区域的标记剂 L；所述靶向剂与标记剂 L 连接、 其中，所述靶向剂包括一种或多种取代和/或未取代的有机环化合物。