1,1-dimethylethyl 1,4,5,7-tetrahydro-4-oxo-1-[2-(phenylthio)ethyl]-6H-pyrazolo[3,4-c]pyridine-6-carboxylate | 478627-92-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,1-dimethylethyl 1,4,5,7-tetrahydro-4-oxo-1-[2-(phenylthio)ethyl]-6H-pyrazolo[3,4-c]pyridine-6-carboxylate
• 英文别名: Tert-butyl 4-oxo-1-(2-phenylsulfanylethyl)-5,7-dihydropyrazolo[3,4-c]pyridine-6-carboxylate
• CAS: 478627-92-8
• 化学式: C₁₉H₂₃N₃O₃S
• 分子量: 373.476
• InChiKey: YSAPUHBHHNWLLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  89.7
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Novel heterocyclic compounds, method for preparing same and use thereof as medicines, in particular as antibacterial agents
  申请人：Aszodi Joseph

  公开号：US20050245505A1

  公开（公告）日：2005-11-03

  The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds, as well as their use as medicaments, in particular as anti-bacterial agents.

  这项发明涉及一般式(I)的新杂环化合物及其与碱或酸形成的盐： 该发明还涉及制备这些化合物的方法，以及它们作为药物的用途，特别是作为抗菌剂。
• Novel heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
  申请人：AVENTIS PHARMA S.A.

  公开号：US20040157826A1

  公开（公告）日：2004-08-12

  The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: 1 The invention also relates to a method for preparing these compounds, and to their use as medicaments, in particular as antibacterials and &bgr;-lactamase inhibitors.

  这项发明涉及一般式(I)的新异环化合物及其与碱或酸的盐：1。该发明还涉及制备这些化合物的方法，并将它们用作药物，特别是作为抗菌药物和β-内酰胺酶抑制剂。
• NOVEL HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTIBACTERIALS AND BETA-LACTAMASE INHIBITORS
  申请人：Lampilas Maxime

  公开号：US20090018329A1

  公开（公告）日：2009-01-15

  The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a method for preparing these compounds, and to their use as medicaments, in particular as antibacterials and β-lactamase inhibitors.

  该发明涉及一种新型杂环化合物，其通式为（I），以及它们与酸或碱的盐：该发明还涉及一种制备这些化合物的方法，并将其用作药物，特别是作为抗菌剂和β-内酰胺酶抑制剂。
• US7288549B2
  申请人：——

  公开号：US7288549B2

  公开（公告）日：2007-10-30
• US7439253B2
  申请人：——

  公开号：US7439253B2

  公开（公告）日：2008-10-21