2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;sulfuric acid | 282102-50-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;sulfuric acid
• CAS: 282102-50-5
• 化学式: C26H31NO5S
• 分子量: 469.6
• InChiKey: LXBHJFOHPWXIGV-OQKDUQJOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.34
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  95.4
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• [EN] PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF DISEASED TISSUES<br/>[FR] COMPOSITIONS PHARMACEUTIQUES DESTINEES AU TRAITEMENT DES TISSUS MALADES
  申请人：LEE CLARENCE C

  公开号：WO2000040269A2

  公开（公告）日：2000-07-13

  A method to treat diseased tissue is provided where a cytotoxic compound is administered to a patient in need of treatment in combination with an immunostimulant. Diseased cells and/or infectious microbes/viruses are killed by the cytotoxic compound in the presence of the immunostimulant. The cell components including cellular contents and cell membrane fragments are presented by the immunostimulant to the host animal as antigens to stimulate the immune responses toward other diseased cells of the same type(s), that either remain in the vicinity or reside in distant tissues or organs. The cytotoxic molecule and immunostimulant are preferably applied locally at high concentrations, either sequentially or, preferably, simultaneously. For example, the composition can be administered directly to a target cancer. The composition can be prepared in various forms, such as a paste, a time release molded solid shape, a solution, a mixture with emulsifier, etc. Alternatively, the cytotoxic molecule and immunostimulant are applied in sequence.