| 1242142-78-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• CAS: 1242142-78-4
• 化学式: C₂₇H₂₅NO₉
• 分子量: 507.497
• InChiKey: YHQRJGIDTZXVGO-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  丁炔二酸二甲酯 、 3-[2-(1,4-benzodioxino)]-4-(tert-butoxycarbonyl)-4H-1,4-benzoxazine 以 甲苯 为溶剂， 反应 4.0h， 以85%的产率得到
  参考文献：
  名称：

  Benzoxazine and Benzodioxine as Indole Isosteres in Indolocarbazoles Series: Synthesis and Biological Evaluation

  摘要：

  New series of structure based on original benzodioxine and benzoxazine heterocycles were prepared leading to potential anticancer lead compounds. In this paper, we described a convenient approach via a Diels-Alder cycloaddition in order to efficiently provide three new indole isosteres in indolocarbazoles series. Their first cytotoxic evaluation was also reported.

  DOI：

  10.2174/157017810790796291