N-(furan-2-ylmethyl)-N-methylnaphthalene-1-sulfonamide | 1023048-35-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-(furan-2-ylmethyl)-N-methylnaphthalene-1-sulfonamide
• CAS: 1023048-35-2
• 化学式: C₁₆H₁₅NO₃S
• 分子量: 301.366
• InChiKey: QVLXLUBPTYLANF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  58.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  以 甲醇 为溶剂， 反应 96.0h， 以75%的产率得到dimethyl 1-((N-methyl-(5-dimethylaminonaphthalene-1-sulfonamido))methyl)-3(exo)-methoxy-7-oxanorborn-5-ene-2(endo),3(endo)-dicarboxylate
  参考文献：
  名称：

  Aqueous-Phase Deactivation and Intramolecular [2 + 2 + 2] Cycloaddition of Oxanorbornadiene Esters

  摘要：

  Both inter- and intramolecular degradation pathways were identified for the aqueous phase deactivation of oxanorbornadiene (OND) electrophiles, and propargylic OND esters were found to undergo facile intramolecular [2 + 2 + 2] homo-Diels-Alder cycloaddition in polar media.

  DOI：

  10.1021/ol103153f

文献信息

• Aqueous-Phase Deactivation and Intramolecular [2 + 2 + 2] Cycloaddition of Oxanorbornadiene Esters
  作者：Alexander A. Kislukhin、Cody J. Higginson、M. G. Finn

  DOI：10.1021/ol103153f

  日期：2011.4.1

  Both inter- and intramolecular degradation pathways were identified for the aqueous phase deactivation of oxanorbornadiene (OND) electrophiles, and propargylic OND esters were found to undergo facile intramolecular [2 + 2 + 2] homo-Diels-Alder cycloaddition in polar media.