Ph3GeCH(n-C3H7)CH2COOH | 934248-66-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: Ph3GeCH(n-C3H7)CH2COOH
• CAS: 934248-66-5
• 化学式: C₂₄H₂₆GeO₂
• 分子量: 419.059
• InChiKey: KTJFOOVNBFFHCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27.0
• 可旋转键数：
  8.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  37.3
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  Ph3GeCH(n-C3H7)CH2COOH 、 三(对甲基苯基)二溴化锑 在 NEt₃ 作用下， 以 甲苯 为溶剂， 以59%的产率得到[Ph3GeCH(n-C3H7)CH2COO]2(antimony)(p-CH3C6H4)3
  参考文献：
  名称：

  Synthesis, Spectral and In Vitro Biological Studies of Bis‐Triorganogermyl(substituted)propionates of Triarylantimony(V) X‐ray Studies of Triphenylgermyl‐n‐propyl Propionic Acid

  摘要：

  New compounds of Bis-triorganogermyl(substituted) propionates of triarylantimony(V) with general formula (R-1(3)-(GeCHRCH2CO2)-C-2) 2SbAr3 have been synthesized and characterized by various techniques such as elemental analyses; FT-IR, (HNMR)-H-1, (CNMR)-C-13 and mass spectrometry. All these compounds have distorted trigonal bipyramidal geometry around antimony in both solid states as well as in non-coordinated solvents. The single X-ray analysis of precursor triphenylgermyl-n-propyl propionic acid (Ph3GeCH-(n-C3H7)CH2COOH) have revealed dimeric structure of molecule through strong hydrogen bonding in conventional manner in which germanium has slightly distorted tetrahedral geometry. Selected numbers of compounds screened against different strains of bacteria and fungus show good activity.

  DOI：

  10.1080/15533170600862903