5,6-Benzoindazol | 268-64-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5,6-Benzoindazol
• 英文别名: 1(2)H-benzo[f]indazole；benz[f]indazole；Benzo[f]indazole；1H-benzo[f]indazole
• CAS: 268-64-4
• 化学式: C₁₁H₈N₂
• mdl: MFCD18450063
• 分子量: 168.198
• InChiKey: XKDZMKALJIYVNU-UHFFFAOYSA-N

物化性质

• 沸点：
  386.9±11.0 °C(Predicted)
• 密度：
  1.301±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• THE USE OF A GLUCOCORTICOID RECEPTOR II ANTAGONIST TO TREAT DEPRESSION IN PATIENTS TAKING IL-2
  申请人：Corcept Therapeutics, Inc.

  公开号：EP2012796A2

  公开（公告）日：2009-01-14
• USE OF MIFEPRISTONE FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
  申请人：Corcept Therapeutics, Inc.

  公开号：EP2306830A1

  公开（公告）日：2011-04-13
• TREATMENT OF MUSCULAR DYSTROPHY
  申请人：Corcept Therapeutics, Inc.

  公开号：EP2576582A1

  公开（公告）日：2013-04-10
• USE OF A GLUCOCORTICOID RECEPTOR II ANTAGONIST TO TREAT DEPRESSION IN PATIENTS TAKING IL-2
  申请人：Belanoff Joseph

  公开号：US20100179115A1

  公开（公告）日：2010-07-15

  The invention pertains to the discovery that type II glucocorticoid receptor antagonists can be used in methods for reversing or inhibiting the symptoms of depression in patients receiving interleukin-2 treatment.
• Indazole-modified ziegler-natta catalyst system
  申请人：Nagy Sandor

  公开号：US20110082268A1

  公开（公告）日：2011-04-07

  A modified Ziegler-Natta catalyst system, a method for preparing the catalyst system, and a process for polymerizing an olefin in the presence of the catalyst system are disclosed. The catalyst system comprises a titanium or vanadium compound, an aluminum compound, and an indazole. Improved comonomer incorporation and the ability to regulate molecular weight are achieved in the manufacture of polyolefins.