<1-Phenyl-cyclohexyl>-glykolsaeure | 92864-36-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: <1-Phenyl-cyclohexyl>-glykolsaeure
• 英文别名: 2-Hydroxy-2-(1-phenylcyclohexyl)acetic acid
• CAS: 92864-36-3
• 化学式: C₁₄H₁₈O₃
• 分子量: 234.295
• InChiKey: KKPUPBUCOGRSJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• SUBSTITUTED PHENYLCYCLOHEXYLGLYCOLATES
  申请人：Gant Thomas G.

  公开号：US20090247628A1

  公开（公告）日：2009-10-01

  Disclosed herein are substituted phenylcyclohexylglycolate-based muscarinic acetylcholine receptor modulators of Formula I, processes of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.

  本文揭示了基于取代苯基环己基甘醇酸酯的 Formula I 的肌氨酸乙酰胆碱受体调节剂，其制备方法、药物组合物及使用方法。
• [EN] N-ARALKYLCARBONYLDIAMINE COMPOUNDS AND PERSONAL CARE COMPOSITIONS COMPRISING THE SAME<br/>[FR] COMPOSÉS N-ARALKYLCARBONYLDIAMINE ET COMPOSITIONS DE SOINS PERSONNELS LES COMPRENANT
  申请人：UNILEVER PLC

  公开号：WO2016173818A1

  公开（公告）日：2016-11-03

  A personal care composition comprising N-aralkylcarbonyldiamines. When such compounds are used in personal care compositions, they have been unexpectedly shown to enhance cell proliferation and epidermal thickness, traits associated with younger, healthy looking skin.

  一种个人护理组合物，包括N-芳基烷基羰基二胺。当这些化合物用于个人护理组合物中时，它们意外地显示出增强细胞增殖和表皮厚度的特性，这些特性与更年轻、更健康的皮肤有关。
• Method for the treatment or prevention of respiratory disorders with a cyclooxygenase-2 inhibitor in combination with a muscarinic receptor antagonist and compositions therewith
  申请人：Seibert Karen

  公开号：US20050107349A1

  公开（公告）日：2005-05-19

  The present invention relates to a novel method of preventing and/or treating respiratory disorders and respiratory disorder-related complications in a subject by administering to the subject at least one Cox-2 inhibitor in combination with one or more muscarinic receptor antagonists. Compositions, pharmaceutical compositions and kits are also described.

  本发明涉及一种新的方法，通过给予受试者至少一种Cox-2抑制剂和一种或多种肌肉性受体拮抗剂的组合，预防和/或治疗呼吸系统疾病及其相关并发症。还描述了组合物、制药组合物和工具包。
• Method for Treating Overactive Bladders and a Device for Storage and Administration of Topical Oxybutynin Compositions
  申请人：Watson Laboratories, Inc.

  公开号：US20140046275A1

  公开（公告）日：2014-02-13

  The invention relates to a method for treating overactive bladders and a device for storing and administering non-occluded oxybutynin topical compositions.

  本发明涉及一种治疗过度活跃膀胱的方法和一种用于储存和给药未阻塞的氧丁宁局部制剂的装置。
• Method For Treating Overactive Bladders And A Device For Storage And Administration Of Topical Oxybutynin Compositions
  申请人：Gochnour Scott

  公开号：US20100286630A1

  公开（公告）日：2010-11-11

  The invention relates to a method for treating overactive bladders and a device for storing and administering non-occluded oxybutynin topical compositions.

  本发明涉及一种治疗过度活跃膀胱的方法和一种用于存储和管理非阻塞的氧布丁啶局部组成物的装置。