磺基玫瑰精甲烷硫代磺酸酯 | 386229-71-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 中文名称: 磺基玫瑰精甲烷硫代磺酸酯
• 中文别名: S-(-)-高丁宁
• 英文名称: Sulforhodamine methanethiosulfonate
• 英文别名: 2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-(2-methylsulfonylsulfanylethylsulfamoyl)benzenesulfonate
• CAS: 386229-71-6
• 化学式: C30H37N3O8S4
• 分子量: 695.9
• InChiKey: DZJCGEWZGVLAEE-UHFFFAOYSA-N

物化性质

• 熔点：
  >300°C
• 溶解度：
  可溶于DMF、DMSO（轻微）、甲醇（轻微、加热）

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  45
• 可旋转键数：
  12
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  203
• 氢给体数：
  1
• 氢受体数：
  11

文献信息

• INNOVATION TO ASSAY MIXING
  申请人：Bio-Rad Laboratories, Inc.

  公开号：US20150090343A1

  公开（公告）日：2015-04-02

  Methods, articles of manufacture, and kits for calibrating fluid delivery systems are provided. A fluid delivery system connected to N input streams, where N is an integer greater than or equal to 2, mixes together fluid from the N input streams to form an output stream. The methods involve obtaining N test solutions, each containing a dye, providing optical absorbances of the test solutions at appropriate wavelengths, injecting the test solutions into the input streams, mixing the test solutions, and measuring the absorbance of the output stream at the same wavelengths. The methods also involve comparing the absorbances of the test solutions with the absorbances of the output stream, which can include calculating ratios and comparing the ratios with target values. The methods can further involve adjusting operation of the fluid delivery system based upon the absorbances. In some embodiments, the dyes have largely non-overlapping absorbance spectra.
• LIGAND IONOPHORE CONJUGATES
  申请人：PURDUE RESEARCH FOUNDATION

  公开号：US20180154006A1

  公开（公告）日：2018-06-07

  The invention described herein pertains to ligand-ionophore conjugates, that may also comprise a linked therapeutic agent or imaging agent, and pharmaceutical compositions containing the conjugates. Also described are methods of using the conjugates for increasing the endosomal accumulation and escape of a therapeutic agent, or an imaging agent.
• US9766213B2
  申请人：——

  公开号：US9766213B2

  公开（公告）日：2017-09-19