4-oxo-N-(tetrahydropyran-4-ylmethyl)chromene-2-carboxamide | 2170696-49-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 4-oxo-N-(tetrahydropyran-4-ylmethyl)chromene-2-carboxamide
• 英文别名: 4H-1-Benzopyran-2-carboxamide, 4-oxo-N-[(tetrahydro-2H-pyran-4-yl)methyl]-；N-(oxan-4-ylmethyl)-4-oxochromene-2-carboxamide
• CAS: 2170696-49-6
• 化学式: C₁₆H₁₇NO₄
• 分子量: 287.315
• InChiKey: IZYIDNNGPAWPMQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  64.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• ANTI-INFECTIVE AGENTS
  申请人：University of Dundee

  公开号：US20190225592A1

  公开（公告）日：2019-07-25

  The present invention relates to a novel class of chromene-2-carboxamide compounds inhibitors of general formula (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and X are as defined herein, to their use in medicine, and their use as anti-infective agents in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.