2-(2'-hydroxyhexadecanoyl)aminooctadecan-1,3-diol | 54482-09-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 鞘脂
• 英文名称: 2-(2'-hydroxyhexadecanoyl)aminooctadecan-1,3-diol
• 英文别名: 2-[(2'-hydroxyhexadecanoyl)amino]octadecane-1,3-diol；2-N-[2-hydroxypalmitoyl]aminooctadecane-1,3-diol；-2-(N-[2-hydroxypalmitoyl]amino)octadecane-1,3-diol；2-N-(2-hydroxyhexadecanoyl)amino-1,3-octadecanediol；2-N-[2-hydroxy-palmitoyl]-amino-octadecane-1,3-diol；2-(2'-hydroxyhexadecanoyl)aminooctadecane-1,3-diol；N-(1,3-dihydroxyoctadecan-2-yl)-2-hydroxyhexadecanamide
• CAS: 54482-09-6
• 化学式: C₃₄H₆₉NO₄
• 分子量: 555.926
• InChiKey: NQXMVCBJWMTLGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.6
• 重原子数：
  39
• 可旋转键数：
  31
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  89.8
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-羟基十六烷酸 、 2-氨基十八烷-1,3-二醇 在 乙醇 作用下， 以 乙酸乙酯 、 正庚烷 为溶剂， 反应 0.25h， 以were obtained with a yield of 70%的产率得到2-(2'-hydroxyhexadecanoyl)aminooctadecan-1,3-diol
  参考文献：
  名称：

  Process for the preparation of ceramide-type compounds

  摘要：

  一种通过将氨基醇与具有定义结构的羧酸反应制备鞘磷酯类化合物的方法，其中反应在微波辐射下进行，温度小于或等于180℃。

  公开号：

  US06017426A1

文献信息

• Rheology modifier/hair styling resin
  申请人：Drzewinski Michael

  公开号：US20060084586A1

  公开（公告）日：2006-04-20

  A rheology modifier/hair styling resin which is a crosslinked, linear poly(vinyl amide/polymerizable carboxylic acid) copolymer exhibits advantageous hair care properties of high viscosity and long-lasting curl retention.

  一种流变改性剂/头发造型树脂，它是一种交联的、线性的聚（乙烯酰胺/可聚合的羧酸）共聚物，展现出高粘度和持久卷曲保持性的优良护发特性。
• [EN] HEMI-AMINAL ETHERS AND THIOETHERS OF N-ALKENYL CYCLIC COMPOUNDS<br/>[FR] ÉTHERS ET THIOÉTHERS HÉMIAMINAUX DE COMPOSÉS CYCLIQUES N-ALCÉNYLIQUES
  申请人：ISP INVESTMENTS INC

  公开号：WO2014116560A1

  公开（公告）日：2014-07-31

  Described herein are hemi-aminal ethers and thioethers of N-alkenyl cyclic compounds that may be produced through a reaction comprising: (A) at least one first reactant represented by a structure (I), wherein X is a functionalized or unfunctionalized C1-C5 alkylene group optionally having one or more heteroatoms, and each R1, R2, and R3 is independently selected from the group consisting of hydrogen and functionalized and unfunctionalized alkyl groups optionally having one or more heteroatoms, and (B) at least one second reactant having at least one hydroxyl moiety or thiol moiety. The hemi-aminal ethers and thioethers of N-alkenyl cyclic compounds may comprise a polymerizable moiety, in which case they may be left as-is or used to create homopolymers or non-homopolymers, or they may not comprise a polymerizable moiety. A wide variety of formulations may be created using the hemi-aminal ethers and thioethers of N-alkenyl cyclic compounds, including personal care, oilfield, and construction formulations.

  本文描述了可以通过反应制备的N-烯基环状化合物的半胺醚和硫醚，所述反应包括：（A）至少一个由结构（I）表示的第一反应物，其中X是一个官能化或非官能化的C1-C5烷基烯烃基团，可选地具有一个或多个杂原子，每个R1、R2和R3分别独立地选自氢和官能化和非官能化的烷基基团，可选地具有一个或多个杂原子；和（B）至少一个具有至少一个羟基基团或硫醇基团的第二反应物。N-烯基环状化合物的半胺醚和硫醚可能包括一个可聚合的基团，此时它们可以保持原样或用于制备同聚物或非同聚物，或者它们可能不包括可聚合的基团。可以使用N-烯基环状化合物的半胺醚和硫醚制备各种配方，包括个人护理、油田和建筑配方。
• Sun protection compositions comprising semi-crystalline polymers and hollow latex particles
  申请人：Candau Didier

  公开号：US20090041691A1

  公开（公告）日：2009-02-12

  Topically applicable cosmetic/dermatological UV protection compositions having enhanced SPF contain at least one organic UV screening agent and/or at least one inorganic screening agent, such compositions also containing at least the following constituents (A) and (B): A) a semi-crystalline polymer which is solid at ambient temperature and has a melting point of greater than or equal to 30° C., containing a) a polymeric backbone and b) at least one crystallizable organic side chain and/or one crystallizable organic block forming part of the backbone of this said polymer, said polymer having a number-average molecular mass Mn of greater than or equal to 1,000, and B) hollow latex particles having a particle size ranging from 150 to 380 nm, formulated into a topically applicable, physiologically acceptable medium therefor.

  具有增强SPF的适用于化妆品/皮肤科的防紫外线保护组合物至少包含一种有机紫外线过滤剂和/或至少一种无机过滤剂，此类组合物还至少包含以下成分（A）和（B）： A）半结晶聚合物，室温下为固体，熔点大于或等于30°C，包含a）聚合骨架和b）至少一种可结晶有机侧链和/或作为该聚合物骨架一部分的可结晶有机块，该聚合物具有大于或等于1,000的数均分子质量Mn，以及 B）中空乳胶颗粒，粒径范围为150至380纳米，配制成适用于局部使用的、生理上可接受的介质。
• Detergent cosmetic compositions containing an anionic surfactant derived from amino acids and salts thereof and an insoluble conditioning agent and uses thereof
  申请人：L'OREAL

  公开号：US20020183217A1

  公开（公告）日：2002-12-05

  Novel detergent cosmetic compositions comprising, in a cosmetically acceptable medium, (a) at least one anionic surfactant chosen from the N-acylated compounds of mono- and polyamidated polycarboxylic amino acids and the salts of said acids and (b) at least one insoluble conditioning agent. This combination imparts at least one of the cosmetic properties of sleekness, lightness and softness while minimizing keratinous fiber regreasing phenomenon. These compositions are used, for example, for washing and/or conditioning a keratinous material such as the hair and the skin.

  含有新型洗涤剂的化妆品组合物，包括在一种适合化妆的介质中，(a) 至少一种阴离子表面活性剂，选择自单和多酰化聚羧基氨基酸的N-酰化化合物和该酸的盐，以及(b) 至少一种不溶性调理剂。这种组合物赋予了至少一种化妆特性，如光滑、轻盈和柔软，同时最大程度地减少角质纤维再油化现象。这些组合物例如用于洗涤和/或调理角质材料，如头发和皮肤。
• Composition for treating keratinous materials comprising a cationic associative polyurethane polymer and a protecting or conditioning agent
  申请人：——

  公开号：US20040037796A1

  公开（公告）日：2004-02-26

  The invention concerns a composition for treating keratinous fibres, in particular human keratinous fibres such as hair, comprising in a physiologically acceptable medium, at least a protecting or conditioning agent, and further at least a cationic associative polyurethane polymer. The invention also concerns methods and devices using said composition.

  这项发明涉及一种用于处理角蛋白纤维的组合物，特别是人类角蛋白纤维，如头发，包括在生理上可接受的介质中，至少一种保护或调理剂，以及至少一种阳离子缔合聚氨酯聚合物。该发明还涉及使用所述组合物的方法和设备。