3-(4-Ethoxyanilino)-1-naphthalen-2-ylpropan-1-ol | 1146191-05-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-(4-Ethoxyanilino)-1-naphthalen-2-ylpropan-1-ol
• CAS: 1146191-05-0
• 化学式: C₂₁H₂₃NO₂
• 分子量: 321.419
• InChiKey: DLCRALMGTSUWDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  41.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• SUBSTITUTED ARYL ALKYLAMINO-OXY-ANALOGS AND USES THEREOF
  申请人：Augelli-Szafran Corinne Elizabeth

  公开号：US20100286164A1

  公开（公告）日：2010-11-11

  Aspects of the invention relate to substituted aryl propylamino-oxy-analogs and uses thereof. Aspects of the invention relate to compositions that are inhibitors of γ-secretase and uses thereof for treating subjects having, or at risk of developing, Alzheimer's disease.

  本发明涉及取代芳基丙氨氧基类似物及其用途。本发明涉及抑制γ-分泌酶的组合物及其用途，用于治疗患有或有患阿尔茨海默病风险的受试者。
• [EN] SUBSTITUTED ARYL ALKYLAMINO-OXY-ANALOGYS AND THEREOF<br/>[FR] ANALOGUES-OXY-ALKYLAMINO ARYLE SUBSTITUÉS ET UTILISATIONS DE CEUX-CI
  申请人：BRIGHAM & WOMENS HOSPITAL

  公开号：WO2009051661A2

  公开（公告）日：2009-04-23

  Aspects of the invention relate to substituted aryl propylamino-oxy-analogs and uses thereof. Aspects of the invention relate to compositions that are inhibitors of γ-secretase and uses thereof for treating subjects having, or at risk of developing, Alzheimer's disease.