2-(8-ethoxy-1,4-dioxo-1,4-dihydro-2-naphthalenyl)-2-methylpropanal | 406923-55-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(8-ethoxy-1,4-dioxo-1,4-dihydro-2-naphthalenyl)-2-methylpropanal
• 英文别名: 2-(8-Ethoxy-1,4-dioxonaphthalen-2-yl)-2-methylpropanal
• CAS: 406923-55-5
• 化学式: C₁₆H₁₆O₄
• 分子量: 272.301
• InChiKey: LUEOULWRAHNSNY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Novel compounds
  申请人：——

  公开号：US20020061921A1

  公开（公告）日：2002-05-23

  The present invention is directed to compounds of formula I, formula Ia, and formula Ib. 1 wherein each of R 1 , R 2 , R 3 , R 4 , R a , and R b has been defined herein. The invention is also directed to a process for the preparation, the use and pharmaceutical compositions comprising the compounds described above. These novel compounds are useful in therapy, particularly for the treatment of type 2 diabetes.

  本发明涉及公式I，公式Ia和公式Ib的化合物。其中，R1，R2，R3，R4，Ra和Rb已在此处定义。本发明还涉及制备过程、使用方法和包括上述化合物的药物组成物。这些新型化合物在治疗方面有用，特别是用于治疗2型糖尿病。
• US6498182B2
  申请人：——

  公开号：US6498182B2

  公开（公告）日：2002-12-24
• [EN] NOVEL COMPOUNDS<br/>[FR] NOUVEAUX COMPOSES
  申请人：BIOVITRUM AB

  公开号：WO2002026707A1

  公开（公告）日：2002-04-04

  The present invention is directed to compounds of formula (I), formula (Ia), and formula (Ib). Wherein each of R?1, R2, R3, R4, Ra, and Rb¿ has been defined herein. The invention is also directed to a process for the preparation, the use and pharmaceutical compositions comprising the compounds described above. These novel compounds are useful in therapy, particularly for the treatment of type 2 diabetes.