Pd(Me2NCS2)(cyclobutylamine)Cl | 252892-73-2

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代酰胺
• 英文名称: Pd(Me2NCS2)(cyclobutylamine)Cl
• 英文别名: chloropalladium(1+);cyclobutanamine;N,N-dimethylcarbamodithioate
• CAS: 252892-73-2
• 化学式: C₇H₁₅ClN₂PdS₂
• 分子量: 333.214
• InChiKey: WBRYIACGGDQEOY-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -2.12
• 重原子数：
  13.0
• 可旋转键数：
  0.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  29.26
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  [Pd(Me2NCS2)Cl]n 、 环丁基胺 以 二氯甲烷 为溶剂， 生成 Pd(Me2NCS2)(cyclobutylamine)Cl
  参考文献：
  名称：

  Palladium and platinum dithiocarbamato complexes containing mono- and diamines

  摘要：

  The [M(DMDT)X](n) (M=Pd or Pt; DMDT=Me2NCS2-; X=Cl or Br) species have been reacted with various amines (Py, pyridine; Pra, n-propylamine; Cba, cyclobutylamine; Dap, 1,3-diaminopropane; En, ethylenediamine) in dichloromethane with the aim of obtaining mixed complexes of various stoichiometries. Along with the neutral complexes M(DMDT)(L)X (L=Py, Pra or Cba), the ionic species IM(DMDT)(L,)IX, [M(DMDT)(En)]X and [M(DMDT)(Dap)]X have been isolated, which have been characterised by IR and proton NMR spectroscopy. Thermogravimetric data suggest a particular behaviour for the palladium-Pra and palladium-Cba derivatives, with formation of low-stoichiometry intermediates of formula Pd-2(DMDT)(2)AmX2. The behaviour of the prepared complexes in various solvents has been described on the basis of the proton NMR spectra. All complexes have been tested for in vitro cytostatic activity against KB cells. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0277-5387(99)00197-7