5-brom-1-thionaphthol | 50638-05-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-brom-1-thionaphthol
• 英文别名: 5-Brom-1-mercapto-naphthalin；5-bromonaphthalen-1-thiol；5-Bromonaphthalene-1-thiol
• CAS: 50638-05-6
• 化学式: C₁₀H₇BrS
• 分子量: 239.136
• InChiKey: JDUYIQXKSCJQOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  5-brom-1-thionaphthol 在 sodium hydroxide 、 nickel dibromide 作用下， 以 水 为溶剂， 反应 0.5h， 生成 1-(5-thiomethylnaphthalin)-phosphonsaeurediethylester
  参考文献：
  名称：

  Horner, Leopold; Flemming, Hans-Wolfram, Phosphorus and Sulfur and the Related Elements, 1984, vol. 19, p. 345 - 362

  摘要：

  DOI：
• 作为产物：
  描述：

  5-bromo-1-naphthalene-sulfonyl chloride 在 盐酸 、 tin 作用下， 反应 0.5h， 以21%的产率得到5-brom-1-thionaphthol
  参考文献：
  名称：

  Horner, Leopold; Flemming, Hans-Wolfram, Phosphorus and Sulfur and the Related Elements, 1984, vol. 19, p. 345 - 362

  摘要：

  DOI：

文献信息

• [EN] TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES<br/>[FR] COMPOSÉS DE TÉTRAZOLINONE ET LEUR UTILISATION EN TANT QUE PESTICIDES
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2013162072A1

  公开（公告）日：2013-10-31

  The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, or a C3-C12 cycloalkyl group, etc., which each optionally be substituted; R2, R3, R4 and R5 represent independently of each other a hydrogen atom, a halogen atom or an C1-C3 alkyl group, etc.; R6 represents an C1-C6 alkyl group, a C3-C6 cycloalkyl group, a halogen atom, a C1-C6 haloalkyl group, an C2-C6 alkenyl group, an C1-C6 alkoxy group, or a C1-C6 haloalkoxy group, etc.; R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, or an C1-C4 alkyl group, etc.; X represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.

  本发明提供了一种具有优异杀虫效果的化合物。公式（1）的四唑酮化合物：[其中R1代表C6-C16芳基、C1-C12烷基或C3-C12环烷基等，每个都可以选择性地被取代；R2、R3、R4和R5分别独立地代表氢原子、卤素原子或C1-C3烷基等；R6代表C1-C6烷基、C3-C6环烷基、卤素原子、C1-C6卤代烷基、C2-C6烯基、C1-C6烷氧基或C1-C6卤代烷氧基等；R7、R8和R9分别独立地代表氢原子、卤素原子或C1-C4烷基等；X代表氧原子或硫原子；R10代表C1-C6烷基等]在杀虫方面表现出优异的控制效果。
• [EN] TETRAZOLINONE COMPOUNDS AND ITS USE<br/>[FR] COMPOSÉS DE TÉTRAZOLINONE ET LEUR UTILISATION
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2013162077A1

  公开（公告）日：2013-10-31

  The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein, R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, a C3-C12 cycloalkyl group or an adamantyl group, etc., which each optionally be substituted; R2 represents a hydrogen atom, an C1-C12 alkyl group, or a halogen atom, etc.; R4 and R5 represent independently of each other a hydrogen atom or an C1-C3 alkyl group, etc.; R6, R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, an C1-C12 alkyl group, a C1-C12 haloalkyl group, an C2-C12 alkenyl group, a C3-C12 cycloalkyl group, an C1-C12 alkoxy group or a C1-C12 haloalkoxy group, etc.; X and Y represent independently of each other a sulfur atom or an oxygen atom; Q represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.

  本发明提供了一种具有优异杀虫效果的化合物。式（1）中的四氮杂酮化合物：[其中，R1代表一个C6-C16芳基，一个C1-C12烷基，一个C3-C12环烷基或一个金刚烷基等，每个都可以选择性地被取代；R2代表一个氢原子，一个C1-C12烷基或一个卤素原子等；R4和R5分别独立地代表一个氢原子或一个C1-C3烷基等；R6、R7、R8和R9分别独立地代表一个氢原子，一个卤素原子，一个C1-C12烷基，一个C1-C12卤代烷基，一个C2-C12烯基，一个C3-C12环烷基，一个C1-C12烷氧基或一个C1-C12卤代烷氧基等；X和Y分别独立地代表一个硫原子或一个氧原子；Q代表一个氧原子或一个硫原子；R10代表一个C1-C6烷基等]对害虫有极佳的控制效果。
• Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal
  申请人：Koh Tze-tzun John

  公开号：US20080064757A1

  公开（公告）日：2008-03-13

  Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor.

  本文披露了雄激素受体及与当前处方的抗雄激素治疗失败相关的雄激素受体突变体的新型拮抗剂，并且使用该拮抗剂治疗与雄激素受体不适当激活相关的疾病。
• Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal
  申请人：Koh John Tze-tzun

  公开号：US20090270512A1

  公开（公告）日：2009-10-29

  Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor.

  本文披露了一些新的雄激素受体拮抗剂以及与当前处方的抗雄激素治疗失败有关的雄激素受体突变体，并使用这些拮抗剂治疗与不适当激活雄激素受体相关的疾病。
• TETRAZOLINONE COMPOUNDS AND ITS USE
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20150031733A1

  公开（公告）日：2015-01-29

  The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein, R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, a C3-C12 cycloalkyl group or an adamantyl group, etc., which each optionally be substituted; R2 represents a hydrogen atom, an C1-C12 alkyl group, or a halogen atom, etc.; R4 and R5 represent independently of each other a hydrogen atom or an C1-C3 alkyl group, etc.; R6, R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, an C1-C12 alkyl group, a C1-C12 haloalkyl group, an C2-C12 alkenyl group, a C3-C12 cycloalkyl group, an C1-C12 alkoxy group or a C1-C12 haloalkoxy group, etc.; X and Y represent independently of each other a sulfur atom or an oxygen atom; Q represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.

  本发明提供了一种具有优异的杀虫功效的化合物。公式（1）的四唑酮化合物：[其中，R1代表C6-C16芳基，C1-C12烷基，C3-C12环烷基或金刚烷基等，每个都可以选择性地被取代；R2代表氢原子，C1-C12烷基或卤素原子等；R4和R5分别独立地代表氢原子或C1-C3烷基等；R6、R7、R8和R9分别独立地代表氢原子、卤素原子、C1-C12烷基、C1-C12卤代烷基、C2-C12烯基、C3-C12环烷基、C1-C12烷氧基或C1-C12卤代烷氧基等；X和Y分别独立地代表硫原子或氧原子；Q代表氧原子或硫原子；R10代表C1-C6烷基等]在控制害虫方面表现出优异的效果。