17,17-Difluoro-1',1',5',5',18-pentamethylspiro[16-oxa-18-azapentacyclo[11.7.0.02,10.03,8.015,19]icosa-1(20),2(10),3,5,7,11,13,15(19)-octaene-9,3'-cyclohexane]-12-ol | 1262590-09-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 17,17-Difluoro-1',1',5',5',18-pentamethylspiro[16-oxa-18-azapentacyclo[11.7.0.02,10.03,8.015,19]icosa-1(20),2(10),3,5,7,11,13,15(19)-octaene-9,3'-cyclohexane]-12-ol
• CAS: 1262590-09-9
• 化学式: C₂₈H₂₉F₂NO₂
• 分子量: 449.541
• InChiKey: JLMUTQLJBOAYIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  33
• 可旋转键数：
  0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  32.7
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• CHROMENE COMPOUND
  申请人：Takahashi Toshiaki

  公开号：US20120270071A1

  公开（公告）日：2012-10-25

  A chromene compound having a skeleton represented by the following formula (1) and exhibiting double peak characteristic: wherein Z is a group represented by any one of the following formulas: n is an integer of 1 to 3, when n is 2 or 3, Z′ s may be the same or different, with the proviso that when n is 1, Z cannot be —CH 2 —, and when n is 2 or 3, Z's cannot be —CH 2 — at the same time; R 1 is an electron absorbing group having a Hammett constant σ p of more than 0, with the proviso that when there are a plurality of R 1 's, R 1 's may be the same or different; and X and Y are each independently an oxygen atom or ═NR 2 , with the proviso that X and Y cannot be oxygen atoms at the same time.