4-chloro-2-[(naphthalene-2-carbonyl)-amino]-benzenesulfonic acid | 1159711-38-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-chloro-2-[(naphthalene-2-carbonyl)-amino]-benzenesulfonic acid
• 英文别名: 4-Chloro-2-(naphthalene-2-carbonylamino)benzenesulfonic acid
• CAS: 1159711-38-2
• 化学式: C₁₇H₁₂ClNO₄S
• 分子量: 361.806
• InChiKey: OLVIUQGJLNLDRL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS<br/>[FR] NOUVEAUX DÉRIVÉS DE BENZAMIDE UTILES EN TANT QUE MODULATEURS DES CANAUX POTASSIQUES
  申请人：NEUROSEARCH AS

  公开号：WO2009068509A1

  公开（公告）日：2009-06-04

  This invention relates to novel benzamide derivatives that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.

  这项发明涉及新型苯甲酰胺衍生物，发现它们是钾通道的有效调节剂，因此是治疗对钾通道调节敏感的疾病或疾病的有价值候选药物。
• NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS
  申请人：Nardi Antonio

  公开号：US20100286149A1

  公开（公告）日：2010-11-11

  This invention relates to novel benzamide derivatives that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels.

  本发明涉及新型苯甲酰胺衍生物，这些衍生物被发现是钾通道的有效调节剂，因此是治疗对钾通道调节敏感的多种疾病或障碍的有价值的候选药物。