(+-)-2-(2-methylbutyl)naphthalene | 30249-66-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (+-)-2-(2-methylbutyl)naphthalene
• 英文别名: 2-(2-Methyl-butyl)-naphthalin；2-<2-Methyl-butyl>-naphthalin；2-(2-Methylbutyl)naphthalene
• CAS: 30249-66-2
• 化学式: C₁₅H₁₈
• 分子量: 198.308
• InChiKey: LEVGNQPKCSIALC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-溴甲基萘 生成 (+-)-2-(2-methylbutyl)naphthalene
  参考文献：
  名称：

  PHOSPHINE-UREA LIGANDS FOR TRANSITION METAL CATALYZED CROSS-COUPLING REACTIONS

  摘要：

  Carbon-carbon bond forming reactions are the cornerstone of organic chemistry. A new class of ligands was developed for transition metal catalyzed cross-coupling reactions. These phosphine-urea ligands incorporate a urea subunit into the backbone of the ligand, which is designed to bind to the organometallic coupling partner and simultaneously facilitate and direct transmetalation of the nucleophile. Synthetic routes were designed and executed to synthesize phosphine-urea ligands. These ligands catalyze a wide variety of cross-coupling reactions including Suzuki, Negishi, and Buchwald-Hartwig cross-couplings. Aryl-aryl, alkyl-aryl, and alkyl-alkyl C—C cross-couplings are performed successfully with these ligands. In addition, specific chiral phosphine-urea ligands catalyze Negishi cross-couplings enantioselectively from a racemic alkylzinc nucleophile.

  公开号：

  US20240218002A1