| 1312204-75-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1312204-75-3
• 化学式: C₂₅H₂₁N₃O₂
• 分子量: 395.461
• InChiKey: RHYQWSLIWFXNFW-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  1-萘胺 在 三乙胺 作用下， 以 乙醇 为溶剂， 反应 10.0h， 生成
  参考文献：
  名称：

  Synthesis of Functionalized 2-Aminohydropyridines and 2-Pyridinones via Domino Reactions of Arylamines, Methyl Propiolate, Aromatic Aldehydes, and Substituted Acetonitriles

  摘要：

  An efficient and practical synthetic method for the functionalized 2-amino hydropyridines and 2-pyridinones was successfully developed via the domino reactions of arylamines, methyl propiolate, aromatic aldehydes and the substituted acetonitriles with triethylamine as base catalyst. Reactions involving malononitrile and cyanoacetamide gave exclusively the 2-aminohydropyridines. On the other hand ethyl cyanoacetate resulted in the 2-pyridinones as main products.

  DOI：

  10.1021/co200071v