xanthene-9-sulfonic acid | 100374-60-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: xanthene-9-sulfonic acid
• 英文别名: Xanthen-9-sulfonsaeure；9H-xanthene-9-sulfonic acid
• CAS: 100374-60-5
• 化学式: C₁₃H₁₀O₄S
• 分子量: 262.286
• InChiKey: KRRPIMGSDORWIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  72
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  占吨醇 在 sodium sulfite 作用下， 生成 xanthene-9-sulfonic acid
  参考文献：
  名称：

  Erdtman; Spetz, Acta Chemica Scandinavica (1947), 1956, vol. 10, p. 1427,1430

  摘要：

  DOI：

文献信息

• [EN] AMIDE-SUBSTITUTED XANTHENE DYES<br/>[FR] TEINTES DE XANTHÈNE À SUBSTITUTION AMIDE
  申请人：EPOCH BIOSCIENCES INC

  公开号：WO2009046165A1

  公开（公告）日：2009-04-09

  The present invention provides amide-substituted xanthene fluorescent dyes and reagent for the introduction of phosphonate or sulfo groups into the fluorescent dyes.

  本发明提供了酰胺取代的蒽醌荧光染料以及用于将膦酸酯或磺酸基团引入荧光染料中的试剂。
• Fluorogenic/Fluorescent Probes Derivative from Sulfoxanthene, and Use Thereof
  申请人：bioMérieux

  公开号：US20160146814A1

  公开（公告）日：2016-05-26

  The invention relates to fluorescent/fluorogenic probes of formula (I″) or (II″): wherein Z is chosen between: —NH 2 and —OH, or in the fluorescence quencher group consisting of: —NO 2 ; —N═N—R 1 ; R 1 being any organic group that does not obscure the corresponding azo bond; —NHCO-Pept.; Pept. being a peptide residue or any organic group that does not obscure the corresponding amide bond; —O-Glyc.; Glyc. being a oligoglycoside residue that does not obscure the corresponding glycosidic bond; —O—C(O)—R 2 ; —O—P(O)(OR 2 )(OR 2 ′) and —O—S(O) 2 —R 2 ; R 2 and R 2 ′ being independently a hydrogen atom or an organic group that does not obscure the corresponding ester bond; and R a , R b , R c , R d and R e being independently a hydrogen atom or any organic group that does not obscure the corresponding arylether bond so as not to prevent its possible cleavage by a myeloperoxidase activity. It also relates to the use of these fluorescent/fluorogenic probes, for the detection of an enzyme activity, notably in order to identify/discriminate microorganisms in function of their ability to express particular enzyme activities.

  该发明涉及式(I″)或(II″)的荧光/荧光探针： 其中Z在以下选项中选择：—NH2和—OH，或者在荧光猝灭剂基团中选择：—NO2；—N═N—R1；其中R1是任何不遮挡相应偶氮键的有机基团；—NHCO-Pept.；Pept.是肽残基或任何不遮挡相应酰胺键的有机基团；—O-Glyc.；Glyc.是不遮挡相应糖苷键的寡糖苷残基；—O—C(O)—R2；—O—P(O)(OR2)(OR2′)和—O—S(O)2—R2；其中R2和R2′独立地是氢原子或不遮挡相应酯键的有机基团；以及Ra、Rb、Rc、Rd和Re独立地是氢原子或任何不遮挡相应芳基醚键的有机基团，以便不阻止其可能被髓过氧化酶活性水解。 该发明还涉及这些荧光/荧光探针的用途，用于检测酶活性，特别是为了根据微生物表达特定酶活性的能力来识别/区分微生物。
• Photosensitive element, film unit, photographic process and dyes
  申请人：POLAROID CORPORATION

  公开号：EP0082506B1

  公开（公告）日：1988-06-29
• PHOSPHONIGSÄUREN, -SALZE UND -ESTER, VERFAHREN ZU DEREN HERSTELLUNG UND IHRE VERWENDUNG
  申请人：Clariant Finance (BVI) Limited

  公开号：EP2178891A2

  公开（公告）日：2010-04-28
• AMIDE-SUBSTITUTED XANTHENE DYES
  申请人：Lukhtanov Eugene

  公开号：US20090093612A1

  公开（公告）日：2009-04-09

  The present invention provides amide-substituted xanthene fluorescent dyes and reagent for the introduction of phosphonate or sulfo groups into the fluorescent dyes.