methyl 1-(3,4-dimethoxyphenyl)-2-phenylcycloprop-2-enecarboxylate | 1315466-91-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: methyl 1-(3,4-dimethoxyphenyl)-2-phenylcycloprop-2-enecarboxylate
• CAS: 1315466-91-1
• 化学式: C₁₉H₁₈O₄
• 分子量: 310.35
• InChiKey: HMKXQERECMGEBA-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  苯乙炔 、 methyl 2-diazo-2-(3,4-dimethoxyphenyl)acetate 以 三氟甲苯 为溶剂， 反应 3.0h， 以44%的产率得到methyl 1-(3,4-dimethoxyphenyl)-2-phenylcycloprop-2-enecarboxylate
  参考文献：
  名称：

  Thermally Induced Cycloadditions of Donor/Acceptor Carbenes

  摘要：

  The thermal decomposition of aryldiazoacetates and aryldiazoketones in the absence of a catalyst leads to synthetically useful transformations. The thermal reaction of aryldiazoacetates with alkenes generates cyclopropanes in 68-97% yield and with good diastereoselectivity (up to 19:1 dr) when the aryl substituent is electron-rich. The thermal reaction of aryldiazoketones with alkenes generated cyclobutanones in 71-94% yield and with good diastereocontrol (>= 9:1 dr).

  DOI：

  10.1021/ol201628d