5-hydroxy-2-(dimethylamino)naphthalene | 106323-45-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-hydroxy-2-(dimethylamino)naphthalene
• 英文别名: 6-(dimethylamino)naphthalen-1-ol
• CAS: 106323-45-9
• 化学式: C₁₂H₁₃NO
• 分子量: 187.241
• InChiKey: LUPGNFXGTBYCAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-hydroxy-2-(dimethylamino)naphthalene 、 2-<3-Methyl-benzoyl>-benzoesaeure 生成 3'-(dimethylamino)-9'-methylspiro[2-benzofuran-3,7'-benzo[c]xanthene]-1-one
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
  申请人：Bellott M. Emile

  公开号：US20070110672A1

  公开（公告）日：2007-05-17

  Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.

  用于体内葡萄糖生物传感器的Small Molecule Metabolite Reporters (SMMRs)、传感器组合物及其使用方法被描述。SMMRs包括含有硼酸的小分子，基于黄烷、香豆素、卡波罗司坦和菲内烯，用于监测体内的葡萄糖，优选在皮肤上。
• [EN] CARBOXY X RHODAMINE ANALOGS<br/>[FR] ANALOGUES DE CARBOXY X RHODAMINE
  申请人：PROMEGA CORP

  公开号：WO2013078244A1

  公开（公告）日：2013-05-30

  The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.

  本发明提供了新型荧光染料和包含这些染料的试剂盒，可用于标记各种生物分子、细胞和微生物。本发明还提供了利用荧光染料进行研究和开发、法医鉴定、环境研究、诊断、预后和/或治疗疾病状况的各种方法。
• CARBOXY X RHODAMINE ANALOGS
  申请人：Promega Corporation

  公开号：US20130317207A1

  公开（公告）日：2013-11-28

  The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.

  本发明提供了新型荧光染料和包含它们的试剂盒，这些染料可用于标记各种生物分子、细胞和微生物。本发明还提供了使用这些荧光染料进行研究和开发、法医鉴定、环境研究、诊断、预后和/或治疗疾病状况的各种方法。
• Carboxy X rhodamine analogs
  申请人：PROMEGA CORPORATION

  公开号：US10139400B2

  公开（公告）日：2018-11-27

  The present invention provides novel fluorescent dyes and kits containing the same, which are useful for labeling a wide variety of biomolecules, cells and microorganisms. The present invention also provides various methods of using the fluorescent dyes for research and development, forensic identification, environmental studies, diagnosis, prognosis and/or treatment of disease conditions.

  本发明提供了新型荧光染料和含有这些荧光染料的试剂盒，可用于标记各种生物大分子、细胞和微生物。本发明还提供了将荧光染料用于研究与开发、法医鉴定、环境研究、诊断、预后和/或疾病治疗的各种方法。
• [EN] CONJUGATES INCLUDING A DETECTABLE MOIETY<br/>[FR] CONJUGUÉS COMPRENANT UNE FRACTION DÉTECTABLE
  申请人：VENTANA MED SYST INC

  公开号：WO2022043491A3

  公开（公告）日：2022-08-04