9-(4-bromophenyl)-6,7-dihydroxy-3H-xanthen-3-one | 1061330-47-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 9-(4-bromophenyl)-6,7-dihydroxy-3H-xanthen-3-one
• CAS: 1061330-47-9
• 化学式: C₁₉H₁₁BrO₄
• 分子量: 383.198
• InChiKey: XPMTUTFICIIUND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.74
• 重原子数：
  24.0
• 可旋转键数：
  1.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  70.67
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  (4-bromophenyl)(2,4,5-trihydroxyphenyl)methanone 、 间苯二酚 在 甲烷磺酸 作用下， 反应 4.0h， 以10%的产率得到9-(4-bromophenyl)-6,7-dihydroxy-3H-xanthen-3-one
  参考文献：
  名称：

  Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties

  摘要：

  We have demonstrated the synthesis of regioisomerically pure unsymmetrical xanthene derivatives consisting of three units which can be independently modified to control their physical properties. The photochemical properties of the synthetic unsymmetrical xanthene derivatives were investigated in solution by UV-vis absorption and fluorescence measurements, and their cell imaging properties were examined by confocal laser-scanning microscopy. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2008.06.065