5-Ethyl-2-oxo-1,3-dioxane-5-carboxylic acid | 1181216-85-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 英文名称: 5-Ethyl-2-oxo-1,3-dioxane-5-carboxylic acid
• CAS: 1181216-85-2
• 化学式: C₇H₁₀O₅
• 分子量: 174.15
• InChiKey: AYRSUXUJHZAWRN-UHFFFAOYSA-N

物化性质

• 沸点：
  400.0±38.0 °C(Predicted)
• 密度：
  1.306±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS
  申请人：University of Southern Mississippi

  公开号：EP2262845A1

  公开（公告）日：2010-12-22
• Monomers and Polymers with Covalently - Attached Active Ingredients
  申请人：Kemp Lisa Kay

  公开号：US20090208553A1

  公开（公告）日：2009-08-20

  Methods to form an active agent modified monomer comprising a ring opening cyclic monomer linked to an active agent via a degradable covalent linkage. Methods to form a polymer or copolymer comprising an active agent modified monomer. Methods to form an active agent modified monomer comprising combining a ring opening cyclic monomer with a first functional group (X) and an active agent with a second functional group (Y) to form an active agent modified monomer, wherein the first (X) and second (Y) functional groups are complementary functional groups that form a degradable linkage. The active agent modified monomer can also comprise a non-degradable linkage. The method can form a ring opening cyclic monomer that includes a cyclic carbonate, cyclic epoxide, lactam, lactone, lactide anhydride, cyclic carbamate, cyclic phosphoester, or siloxane. Apparatus that includes a medical device that comprises a polymer or copolymer that comprises an active agent modified monomer.
• ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS
  申请人：International Business Machines Corporation

  公开号：US20170303541A1

  公开（公告）日：2017-10-26

  Antimicrobial cationic polycarbonates and polyurethanes have been prepared comprising one or more pendent guanidinium and/or isothiouronium groups. Additionally, antimicrobial particles were prepared having a silica core linked to surface groups comprising a guanidinium and/or isothiouronium group. The cationic polymers and cationic particles can be potent antimicrobial agents against Gram-negative microbes, Gram-positive microbes, and/or fungi.
• [EN] MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS<br/>[FR] MONOMÈRES ET POLYMÈRES AVEC DES INGRÉDIENTS ACTIFS ATTACHÉS DE FAÇON COVALENTE
  申请人：UNIV SOUTHERN MISSISSIPPI

  公开号：WO2009102795A1

  公开（公告）日：2009-08-20

  Methods to form an active agent modified monomer comprising a ring opening cyclic monomer linked to an active agent via a degradable covalent linkage. Methods to form a polymer or copolymer comprising an active agent modified monomer. Methods to form an active agent modified monomer comprising combining a ring opening cyclic monomer with a first functional group (X) and an active agent with a second functional group (Y) to form an active agent modified monomer, wherein the first (X) and second (Y) functional groups are complementary functional groups that form a degradable linkage. The active agent modified monomer can also comprise a non-degradable linkage. The method can form a ring opening cyclic monomer that includes a cyclic carbonate, cyclic epoxide, lactam, lactone, lactide anhydride, cyclic carbamate, cyclic phosphoester, or siloxane. Apparatus that includes a medical device that comprises a polymer or copolymer that comprises an active agent modified monomer.