2-octadecanoylaminooctadecan-1,3-diol | 96673-02-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 鞘脂
• 英文名称: 2-octadecanoylaminooctadecan-1,3-diol
• 英文别名: 2-(N-stearoylamino)octadecane-1,3-diol；2-N-stearoylaminooctadecane-1,3-diol；N-octadecanoyl-sphinganine；C18:0；2-octadecanoylaminooctadecane-1,3-diol；-2-(N-stearoylamino)octadecane-1,3-diol；N-(1,3-dihydroxyoctadecan-2-yl)octadecanamide
• CAS: 96673-02-8
• 化学式: C₃₆H₇₃NO₃
• 分子量: 567.981
• InChiKey: KZTJQXAANJHSCE-UHFFFAOYSA-N

物化性质

• 熔点：
  106-106.5 °C
• 沸点：
  694.8±45.0 °C(Predicted)
• 密度：
  0.909±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  14.5
• 重原子数：
  40
• 可旋转键数：
  33
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氨基十八烷-1,3-二醇 、 硬脂酸 在 乙醇 作用下， 以 乙酸乙酯 、 正庚烷 为溶剂， 反应 0.3h， 以were obtained with a yield of 72%的产率得到2-octadecanoylaminooctadecan-1,3-diol
  参考文献：
  名称：

  Process for the preparation of ceramide-type compounds

  摘要：

  一种通过将氨基醇与具有定义结构的羧酸反应制备鞘磷酯类化合物的方法，其中反应在微波辐射下进行，温度小于或等于180℃。

  公开号：

  US06017426A1

文献信息

• Detergent cosmetic compositions containing an anionic surfactant derived from amino acids and salts thereof and an insoluble conditioning agent and uses thereof
  申请人：L'OREAL

  公开号：US20020183217A1

  公开（公告）日：2002-12-05

  Novel detergent cosmetic compositions comprising, in a cosmetically acceptable medium, (a) at least one anionic surfactant chosen from the N-acylated compounds of mono- and polyamidated polycarboxylic amino acids and the salts of said acids and (b) at least one insoluble conditioning agent. This combination imparts at least one of the cosmetic properties of sleekness, lightness and softness while minimizing keratinous fiber regreasing phenomenon. These compositions are used, for example, for washing and/or conditioning a keratinous material such as the hair and the skin.

  含有新型洗涤剂的化妆品组合物，包括在一种适合化妆的介质中，(a) 至少一种阴离子表面活性剂，选择自单和多酰化聚羧基氨基酸的N-酰化化合物和该酸的盐，以及(b) 至少一种不溶性调理剂。这种组合物赋予了至少一种化妆特性，如光滑、轻盈和柔软，同时最大程度地减少角质纤维再油化现象。这些组合物例如用于洗涤和/或调理角质材料，如头发和皮肤。
• Composition for treating keratinous materials comprising a cationic associative polyurethane polymer and a protecting or conditioning agent
  申请人：——

  公开号：US20040037796A1

  公开（公告）日：2004-02-26

  The invention concerns a composition for treating keratinous fibres, in particular human keratinous fibres such as hair, comprising in a physiologically acceptable medium, at least a protecting or conditioning agent, and further at least a cationic associative polyurethane polymer. The invention also concerns methods and devices using said composition.

  这项发明涉及一种用于处理角蛋白纤维的组合物，特别是人类角蛋白纤维，如头发，包括在生理上可接受的介质中，至少一种保护或调理剂，以及至少一种阳离子缔合聚氨酯聚合物。该发明还涉及使用所述组合物的方法和设备。
• Composition for treating keratinous materials comprising a cationic poly(alkyl) vinyllactam polymer and a protecting or conditioning agent
  申请人：——

  公开号：US20040131572A1

  公开（公告）日：2004-07-08

  The invention relates to a composition for treating keratin materials, in particular the hair, comprising, in a physiologically and in particular a cosmetically acceptable medium, at least one protecting or conditioning agent, and also at least one cationic poly(alkyl)vinyllactam polymer. These combinations make it possible to improve the deposition of the agent for protecting or conditioning the keratin materials and also the cosmetic properties.

  该发明涉及一种用于处理角蛋白材料，特别是头发的组合物，包括至少一种保护或调理剂，在生理学上特别是在化妆学上可接受的介质中，并且至少一种阳离子聚（烷基）乙烯内酯聚合物。这些组合使得可以改善保护或调理角蛋白材料的剂沉积以及化妆性能。
• Dyeing processes comprising at least one multi-carbosite, multi-group coupling agent for wash-protecting the color of artificially dyed keratin fibers
  申请人：Lalleman Boris

  公开号：US20080313821A1

  公开（公告）日：2008-12-25

  Disclosed herein is a cosmetic process for wash-protecting the color of artificially dyed keratin fibers, comprising applying to the keratin fibers at least one composition comprising at least one multi-carbosite, multi-group coupling agent, the coupling agent being an electrophilic hydrocarbon-based compound comprising neither an aldehyde group, nor a carboxylic acid group, nor a formol-generating group, the coupling agent comprising at least two identical reactive groups, the reactive groups not being carried by the same atom, if said atom is a carbon atom, and the coupling agent having a molecular weight of less than 500 g/mol.

  本文揭示了一种用于保护人工染色角蛋白纤维颜色的化妆过程，包括将至少一种包含至少一种多羟基化合物的组合物应用于角蛋白纤维，该耦合剂是一种电泳烃基化合物，既不包含醛基，也不包含羧酸基，也不包含甲醛生成基团，该耦合剂包括至少两个相同的反应基团，这些反应基团不由同一原子携带，如果该原子是碳原子，则该耦合剂的分子量小于500克/摩尔。
• COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE ANIONIC ASSOCIATIVE POLYMER AND COSMETIC TREATMENT PROCESSES USING SAID COMPOSITION
  申请人：BIGANSKA Olga

  公开号：US20090074692A1

  公开（公告）日：2009-03-19

  The disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable medium: (i) at least one cationic polymer which are produced by polymerization of a mixture of monomers comprising: a) at least one vinyl monomer substituted with at least one amino group, b) at least one hydrophobic nonionic vinyl monomer, c) at least one associative vinyl monomer, and e) at least one hydroxylated nonionic vinyl monomer, and (ii) at least one anionic associative polymers.

  该披露涉及新型化妆品组合物，包括在适合用于化妆的介质中的：(i) 至少一种阳离子聚合物，其由包括：a) 至少一种含有至少一个氨基团的乙烯单体，b) 至少一种疏水非离子乙烯单体，c) 至少一种关联性乙烯单体，和e) 至少一种羟基化非离子乙烯单体的单体混合物聚合而成，以及(ii) 至少一种阴离子关联性聚合物。