γ-mangostin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: γ-mangostin
• 英文别名: 1,3,6,7-tetrahydroxy-2-(3-methylbut-2-enyl)xanthone；1,3,6,7-tetrahydroxy-2-prenylxanthone；1,3,6,7-tetrahydroxy-2-(3-methylbut-2-enyl)xanthen-9-one
• 化学式: C₁₈H₁₆O₆
• 分子量: 328.321
• InChiKey: ACRGTLGOYYTGNX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 γ-mangostin 以 甲醇 、 乙醚 为溶剂， 以100%的产率得到1-hydroxy-3,6,7-trimethoxy-2-(3-methylbut-2-enyl)-xanthone
  参考文献：
  名称：

  A Novel Depsidone and Some New Xanthones from Garcinia Species.

  摘要：

  Constituents of three EtOH extracts of the stem bark of Garcinia assigu LANTB., Garcinia dulcis (ROXB.) KURZ., and Garcinia latissima MIQ., belonging to the Guttiferae, collected in Central Province of Papua New Guinea, were studied. A novel depsidone named garcinisidone-A (1), six new xanthones named assiguxanthone-A (3) and -B (9) and dulxanthone-A (4), -B (6), -C (7), and -D (11), and four new pyranoxanthones named latisxanthone-A (13), -B (14), -C (15), and -D (16) were isolated, as well as some known xanthone, benzophenone, chromone, and biflavanone derivatives, and their structures were elucidated by spectroscopic methods. Among these components, garcinisidone-A (1) is the first example of a depsidone derivative having a five-carbon unit (prenyl) as a substituent to be found in nature. Latisxanthone-B (14) was found to contain a hydroperoxy moiety in the molecule. This is the second example of a xanthone hydroperoxide to be found in nature.

  DOI：

  10.1248/cpb.45.1403