Protoapigenin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: Protoapigenin
• 英文别名: 2-(1,4-dihydroxycyclohexa-2,5-dien-1-yl)-5,7-dihydroxychromen-4-one
• 化学式: C₁₅H₁₂O₆
• 分子量: 288.25
• InChiKey: BXZYQTCXZAHTCI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Methods and compositions for inhibition of ATR and FANCD2 activation
  申请人：Kaohsiung Medical University

  公开号：US10195176B2

  公开（公告）日：2019-02-05

  This invention is announcing a composition of flavonoid skeleton in the formula I or formula II compound, wherein each of the substituents is given the definition as set forth in the specification and claims. This composition have the capacity to treating or preventing a virus infection in a subject.

  本发明公布了一种由式 I 或式 II 化合物中的黄酮类骨架组成的组合物，其中各取代基的定义见说明书和权利要求书。该组合物具有治疗或预防受试者感染病毒的能力。
• METHODS AND COMPOSITIONS FOR INHIBITION OF ATR AND FANCD2 ACTIVATION
  申请人：KAOHSIUNG MEDICAL UNIVERSITY

  公开号：US20130310448A1

  公开（公告）日：2013-11-21

  This invention is announcing a composition of flavonoid skeleton in the formula I or formula II compound, wherein each of the substituents is given the definition as set forth in the specification and claims. This composition have the capacity to Inhibit functions of ATR and FANCD2 on DNA replication, damage checkpoint, and repair; therefore, this composition can improve the cancer sensitivity and poor prognosis to DNA-damaging therapeutics.
• Methods and Compositions for Inhibition of ATR and FANCD2 Activation
  申请人：Kaohsiung Medical University

  公开号：US20160158190A1

  公开（公告）日：2016-06-09

  This invention is announcing a composition of flavonoid skeleton in the formula I or formula II compound, wherein each of the substituents is given the definition as set forth in the specification and claims. This composition have the capacity to treating or preventing a virus infection in a subject.
• US9918962B2
  申请人：——

  公开号：US9918962B2

  公开（公告）日：2018-03-20