6,6,9-Trimethyl-3-(2-phenylethyl)-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 6,6,9-Trimethyl-3-(2-phenylethyl)-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
• 化学式: C₂₄H₂₈O₂
• 分子量: 348.5
• InChiKey: DYHMKBLKWFFFSZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] CATALYTIC CANNABINOID PROCESSES AND PRECURSORS<br/>[FR] PROCÉDÉS ET PRÉCURSEURS DE CANNABINOÏDES CATALYTIQUES
  申请人：KARE CHEMICAL TECH INC

  公开号：WO2020232545A1

  公开（公告）日：2020-11-26

  The present disclosure relates to new cannabinoid sulfonate esters and processes for their use to prepare cannabinoids. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of cannabinoids from the cannabinoid sulfonate esters.

  本公开涉及新的大麻素磺酸酯和它们的制备大麻素的过程。该公开还涉及使用催化剂和催化过程从大麻素磺酸酯制备大麻素。
• METHOD OF PURIFYING CANNABINOIDS FROM YEAST FERMENTATION BROTH
  申请人：Demetrix, Inc.

  公开号：US20210189444A1

  公开（公告）日：2021-06-24

  Provided herein are methods of purifying cannabinoids or cannabinoid derivatives produced using modified host cells and recovering the resulting cannabinoid or cannabinoid derivative preparations. The present methods provide preparations comprising cannabinoids or cannabinoid derivatives having increased purity and amounts of the cannabinoids or cannabinoid derivatives.
• OPTIMIZED CANNABINOID SYNTHASE POLYPEPTIDES
  申请人：Demetrix, Inc.

  公开号：US20220228130A1

  公开（公告）日：2022-07-21

  The present disclosure provides engineered variants of a cannabidiolic acid synthase (CBDAS) polypeptide comprising an amino acid sequence of SEQ ID NO:3 with one or more amino acid substitutions, nucleic acids comprising nucleotide sequences encoding said engineered variants, methods of making modified host cells comprising said nucleic acids, modified host cells expressing said engineered variants, methods of producing cannabinoids or cannabinoid derivatives, and methods of screening engineered variants of the cannabidiolic acid synthase (CBDAS) polypeptide.
• [EN] OPTIMIZED EXPRESSION SYSTEMS FOR PRODUCING CANNABINOID SYNTHASE POLYPEPTIDES, CANNABINOIDS, AND CANNABINOID DERIVATIVES<br/>[FR] SYSTÈMES D'EXPRESSION OPTIMISÉS POUR PRODUIRE DES POLYPEPTIDES DE SYNTHASE DE CANNABINOÏDES, CANNABINOÏDES ET DÉRIVÉS DE CANNABINOÏDES
  申请人：DEMETRIX INC

  公开号：WO2020069214A2

  公开（公告）日：2020-04-02

  The present disclosure provides modified host cells that produce a cannabinoid or a cannabinoid derivative and modified host cells that express a cannabinoid synthase polypeptide. The present disclosure also provides methods of synthesizing a cannabinoid or a cannabinoid derivative. Further, the present disclosure provides novel cannabinoids and cannabinoid derivatives, compositions, including pharmaceutical compositions, as well as methods, uses, compounds for use, medicaments, and compositions (including pharmaceutical compositions) for use comprising said cannabinoid and cannabinoid derivatives.
• [EN] OPTIMIZED CANNABINOID SYNTHASE POLYPEPTIDES<br/>[FR] POLYPEPTIDES DE SYNTHASE CANNABINOÏDE OPTIMISÉS
  申请人：DEMETRIX INC

  公开号：WO2020236789A1

  公开（公告）日：2020-11-26

  The present disclosure provides engineered variants of a cannabidiolic acid synthase (CBDAS) polypeptide comprising an amino acid sequence of SEQ ID NO:3 with one or more amino acid substitutions, nucleic acids comprising nucleotide sequences encoding said engineered variants, methods of making modified host cells comprising said nucleic acids, modified host cells expressing said engineered variants, methods of producing cannabinoids or cannabinoid derivatives, and methods of screening engineered variants of the cannabidiolic acid synthase (CBDAS) polypeptide.