5,5-二乙基-1,3-二恶烷 | 3390-07-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二恶烷
• 中文名称: 5,5-二乙基-1,3-二恶烷
• 英文名称: 5,5-Diaethyl-<1,3>dioxan
• 英文别名: 5,5-Diaethyl-1,3-dioxan；5,5-Diethyl-1,3-dioxane
• CAS: 3390-07-6
• 化学式: C₈H₁₆O₂
• 分子量: 144.214
• InChiKey: PXZBONIIVQBUBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2934999090

文献信息

• ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS
  申请人：SANOFI

  公开号：US20140309264A1

  公开（公告）日：2014-10-16

  The present invention relates to compounds of the formula I, wherein A, Y, Z, R 3 to R 6 , R 20 to R 22 and R 50 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. Specifically, they are inhibitors of the endothelial differentiation gene receptor 2 (Edg-2, EDG2), which is activated by lysophosphatidic acid (LPA) and is also termed as LPA 1 receptor, and are useful for the treatment of diseases such as atherosclerosis, myocardial infarction and heart failure, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.

  本发明涉及公式I的化合物，其中A、Y、Z、R3至R6、R20至R22和R50具有所述权利要求中指示的含义，它们是有价值的药物活性化合物。具体而言，它们是内皮分化基因受体2（Edg-2，EDG2）的抑制剂，该受体被溶血磷脂酸（LPA）激活，也称为LPA1受体，并且对于例如动脉粥样硬化、心肌梗死和心力衰竭等疾病的治疗是有用的。此外，本发明还涉及公式I化合物的制备方法、它们的使用以及包含它们的药物组合物。
• Copolymerisierbare Polyalkylenglykol-Makromonomere, deren Herstellung und Verwendung
  申请人：Clariant Produkte (Deutschland) GmbH

  公开号：EP1584631B1

  公开（公告）日：2008-11-12
• Ink composition
  申请人：Fujifilm Speciality Ink Systems Limited

  公开号：EP2502967B1

  公开（公告）日：2019-08-21
• Method for Recovering Di-Trimethylolpropane By Distillation
  申请人：Oxea GmbH

  公开号：US20140284202A1

  公开（公告）日：2014-09-25

  Distillative process for obtaining ditrimethylolpropane from solutions includes separating ditrimethylolpropane from the solution in a first distillation unit into a first tops fraction comprising low-boiling compounds having a lower boiling point than ditrimethylolpropane and a first bottoms fraction; introducing the first bottoms fraction into a second distillation unit having at least 5 theoretical plates, said unit being configured as a thin-film evaporator with a column attachement and drawing off a second tops fraction comprising intermediate-boiling compounds having a lower boiling point than ditrimethylolpropane as well as withdrawing a second bottoms fraction from the second distillation unit and introducing the second bottoms fraction into a third distillation unit having at least 4 theoretical plates, said unit being configured as a thin-film evaporator with a column attachement, such that ditrimethylolpropane is obtained as a third tops fraction and high boilers are removed as a third bottoms fraction.
• OIL-BASED INKJET INK
  申请人：RISO KAGAKU CORPORATION

  公开号：US20180079854A1

  公开（公告）日：2018-03-22

  An oil-based inkjet ink that exhibits excellent repellency by the nozzle plate, prevents degradation of the nozzle plate, reduces image show-through, and yields high image density. The oil-based inkjet ink includes an encapsulated pigment containing a pigment and a urethane compound that coats the surface of the pigment, and a non-aqueous solvent, wherein the urethane compound has a urethane skeleton and one or more side chains and is insoluble in the non-aqueous solvent, and the side chains of the urethane compound contain one or more moieties selected from the group consisting of an aromatic ring, a heterocyclic ring, a carboxyl group, an amide linkage, a fluoroalkyl group having one or more fluorine atoms, and a nitrile group.