1-(Hydroxymethyl)-2,3,5,6,7,8-hexahydropyrrolizine-1,2-diol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯里西啶类
• 英文名称: 1-(Hydroxymethyl)-2,3,5,6,7,8-hexahydropyrrolizine-1,2-diol
• 化学式: C₈H₁₅NO₃
• 分子量: 173.21
• InChiKey: IDSPCUWITUCFDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  63.9
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS<br/>[FR] COMPOSÉS POUR LE TRAITEMENT D'INFECTIONS FLAVIVIRALES
  申请人：SUMMIT CORP PLC

  公开号：WO2010015815A2

  公开（公告）日：2010-02-11

  Described are various compounds and methods for the treatment of flaviviral infections. In particular, alkaloids and imino sugars in arabinose and/or lyxose stereochemical configuration with antiflaviviral activity are described.
• [EN] TREATMENT OF ENERGY UTILIZATION DISEASES<br/>[FR] TRAITEMENT DE MALADIES UTILISANT DE L'ÉNERGIE
  申请人：SUMMIT CORP PLC

  公开号：WO2010049678A2

  公开（公告）日：2010-05-06

  Described are various compounds, in particular iminosugars, for the treatment of energy utilization diseases, in particular diabetes (including type 1 diabetes, type 2 diabetes and insulin resistance) and metabolic syndrome (including any disease or disorder associated therewith, for example central obesity and elevated levels of triglycerides).