4-Hydroxy-4,7a-dihydrofuro[2,3-b]pyran-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃吡喃类
• 英文名称: 4-Hydroxy-4,7a-dihydrofuro[2,3-b]pyran-2-one
• 英文别名: 4-hydroxy-4,7a-dihydrofuro[2,3-b]pyran-2-one
• 化学式: C₇H₆O₄
• 分子量: 154.12
• InChiKey: IONMZUYDQDQPGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• NEMATODE CONTROL COMPOSITION COMPRISING GRAMMICIN COMPOUND AS ACTIVE INGREDIENT AND USE THEREOF
  申请人：Industry Foundation of Chonnam National University

  公开号：EP3520614A2

  公开（公告）日：2019-08-07

  The present invention relates to a nematode control composition comprising, as an effective ingredient, grammicin isolated from a Xylaria grammica strain, and uses thereof, in which grammicin as a compound for controlling nematode according to the present invention is derived from a natural product so that it is harmless to a human body, does not cause any environmental contamination, and exhibits an excellent control activity against root knot nematodes, and thus it can be advantageously used for developing an environment-friendly natural nematicide and production of a high value-added organic agricultural product. Furthermore, grammicin can be utilized either directly or as a lead compound for developing a chemical for controlling nematode in animal and human. If this technique is developed and transferred to domestic companies to yield production of a biological control product, it can contribute not only to the domestic production of environment-friendly agricultural products but also earning of foreign currencies according to export of the technique to the global market.

  本发明涉及一种线虫防治组合物，其有效成分包括从 Xylaria grammica 菌株中分离出来的克线虫素及其用途，其中克线虫素作为根据本发明防治线虫的化合物是从天然产品中提取的，因此对人体无害、因此，它可被有利地用于开发环境友好型天然杀线虫剂和生产高附加值的有机农产品。 此外，克线虫素既可以直接利用，也可以作为先导化合物用于开发控制动物和人类线虫的化学品。如果这项技术被开发出来并转让给国内公司生产生物防治产品，不仅可以促进国内环保型农产品的生产，还可以通过向全球市场出口该技术赚取外汇。
• Composition for controlling nematode comprising grammicin compound as effective ingredient and uses thereof
  申请人：INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY

  公开号：US11000039B2

  公开（公告）日：2021-05-11

  A method for controlling nematode includes treating a plant or soil with a composition comprising a grammicin compound of Formula 1 or an agriculturally acceptable salt thereof. The grammicin compound may be isolated from a Xylaria grammica strain so that it is harmless to a human body, does not cause any environmental contamination, and exhibits an excellent control activity against root knot nematodes. Thus, it can be advantageously used for developing an environment-friendly natural nematicide and production of a high value-added organic agricultural product.

  一种控制线虫的方法包括用一种包含式 1 的克里克菌素化合物或其农业上可接受的盐的组合物处理植物或土壤。格拉米星化合物可以从 Xylaria grammica 菌株中分离出来，因此对人体无害，不会造成任何环境污染，并且对根结线虫具有极佳的控制活性。因此，它可用于开发环境友好型天然杀线虫剂和生产高附加值的有机农产品。