1-(2-Methoxyphenyl)-3-naphthalen-2-ylurea | 251917-79-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-(2-Methoxyphenyl)-3-naphthalen-2-ylurea
• CAS: 251917-79-0
• 化学式: C₁₈H₁₆N₂O₂
• 分子量: 292.3
• InChiKey: ISADADAHPHHLEM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  50.4
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases
  申请人：Cenix Bioscience GmbH

  公开号：EP1832283A1

  公开（公告）日：2007-09-12

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.

  本发明涉及使用清道夫受体类蛋白，特别是 ScarB1 的抑制剂来生产治疗和/或预防涉及肝细胞和/或造血细胞，特别是疟疾的感染的药物。
• Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases
  申请人：Hannus Michael

  公开号：US20090324580A1

  公开（公告）日：2009-12-31

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.
• USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES
  申请人：HANNUS MICHAEL

  公开号：US20120276121A1

  公开（公告）日：2012-11-01

  The present invention relates to the use of inhibitors of scavenger receptor class proteins, in particular ScarB1 for the production of a medicament for treatment of and/or prophylaxis against infections, involving liver cells and/or hematopoietic cells, in particular malaria.
• INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS
  申请人：Hamblin Michael R.

  公开号：US20130115133A1

  公开（公告）日：2013-05-09

  The present invention relates the use of phenothiaziniums and microbial MDR inhibitors to inactivate microorganisms. Methods of the present invention are useful in the treatment of living subjects and in the decontamination of inanimate objects and substances.
• US8507546B2
  申请人：——

  公开号：US8507546B2

  公开（公告）日：2013-08-13