1-hydroxy-6,8-dimethoxy-3-methylxanthone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 1-hydroxy-6,8-dimethoxy-3-methylxanthone
• 英文别名: dothideoxanthone；1-Hydroxy-6,8-dimethoxy-3-methylxanthone；1-hydroxy-6,8-dimethoxy-3-methylxanthen-9-one
• 化学式: C₁₆H₁₄O₅
• 分子量: 286.284
• InChiKey: LLVZBTTVGJRIPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-hydroxy-6,8-dimethoxy-3-methylxanthone 生成 dothideoisoflavanone
  参考文献：
  名称：

  Isoflavanone and xanthone derivatives from Dothideomycetes fungus CMU-99

  摘要：

  Dothideoisoflavanone, a new isoflavanone, and dothideoxanthone, a new xanthone, along with twelve known metabolites are isolated from the broth extract of the Dothideomycetes fungus CMU-99. Their structures are identified on the basis of spectroscopic data. The isolated compounds are evaluated for their cytotoxic and antimycobacterial activities. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2015.01.088